Senior Researcher, Molecular Biology

Memorial Sloan Kettering Cancer Center•New York, NY

6d•$77,100 - $119,400•Onsite

About The Position

The Olayan Center for Cancer Vaccines at Memorial Sloan Kettering Cancer Center is seeking a Senior Researcher, Molecular Biology, to join its RNA Therapeutics Lab. The role supports the manufacture, characterization, and innovation of mRNA-based personalized cancer vaccines. It focuses on advancing beyond conventional DNA/RNA production and improving platform design and processes. The researcher will help build the lab, shape its workflows, and develop new approaches. The position involves producing mRNA vaccines through in vitro transcription; developing in-house DNA assembly platforms for rapid DNA template production and analytical release; and investigating novel mRNA-based and DNA technologies, including ribozymes, ligation, and mRNA display, for clinical and research applications. The researcher will collaborate with formulation, analytical, research, and GMP teams to optimize mRNA designs and processes. The role also includes analyzing and visualizing data, preparing reports of results and methods, and presenting findings at regular lab meetings. The researcher will maintain, operate, and inventory laboratory instruments and reagents; follow and promote laboratory safety procedures; and train other laboratory personnel as needed. Other duties may be assigned.

Requirements

B.S. in molecular biology, biochemistry, or a related field with 7 years of relevant experience, or an M.S. with 4 years of experience.
Strong molecular biology skills well beyond conventional cloning techniques.
Exceptional attention to detail and strong analytical skills.
Ability to thrive in a fast-paced research environment and manage multiple projects while maintaining precision.
Critical-thinking and problem-solving skills to troubleshoot experimental challenges.
Outstanding interpersonal and communication skills, including the ability to interact across all levels in a confident, concise, and professional manner.
Enthusiasm and dedication to MSK's vision, mission, and values.

Nice To Haves

Ph.D.

Responsibilities

Produce mRNA vaccines using in vitro transcription.
Develop in-house DNA assembly platforms for rapid DNA template production and analytical release.
Investigate and innovate novel mRNA-based and DNA technologies, such as ribozymes, ligation, and mRNA display, for clinical and research applications.
Collaborate with formulation, analytical, research, and GMP teams to pursue optimal mRNA designs and processes.
Analyze data and create graphs using appropriate software and data visualization tools.
Write reports describing results and methods, and present data at regular lab meetings.
Perform routine maintenance, operation, and inventory for laboratory instruments and reagents.
Follow proper safety recommendations and handling procedures for biological and chemical materials, and ensure others in the laboratory follow proper safety procedures.
Train other laboratory personnel as needed.
Perform other duties as assigned.