Senior Researcher, Molecular Biology

Memorial Sloan Kettering Cancer Center•New York, NY

6d•Onsite

About The Position

The Senior Researcher, Molecular Biology will join Memorial Sloan Kettering Cancer Center’s RNA Therapeutics Lab within the Olayan Center for Cancer Vaccines. The role supports the manufacture, characterization, and innovation of mRNA-based personalized cancer vaccines, with a focus on improving conventional DNA and RNA production and advancing platform design and process development. The researcher will help establish the lab, shape workflows, and develop new approaches. The position involves producing mRNA vaccines using in vitro transcription, developing in-house DNA assembly platforms for rapid DNA template production and analytical release, and investigating novel mRNA-based and DNA technologies for clinical and research applications. The researcher will collaborate with formulation, analytical, research, and GMP teams; analyze and present data; maintain laboratory instruments and reagents; follow and promote laboratory safety procedures; and train other personnel as needed. The role is onsite in New York City and reports to the Associate Director.

Requirements

Bachelor’s degree in molecular biology, biochemistry, or a related field with 7 years of relevant experience, or a master’s degree with 4 years of experience.
Strong molecular biology skills well beyond conventional cloning techniques.
Exceptional attention to detail and strong analytical skills.
Ability to thrive in a fast-paced research environment, manage multiple projects, and maintain precision.
Critical-thinking and problem-solving skills to troubleshoot experimental challenges.
Outstanding interpersonal and communication skills, including the ability to interact across all levels in a confident, concise, and professional manner.
Enthusiasm and dedication to MSK’s vision, mission, and values.

Nice To Haves

Ph.D.

Responsibilities

Produce mRNA vaccines using in vitro transcription.
Develop in-house DNA assembly platforms for rapid DNA template production and analytical release.
Investigate and innovate novel mRNA-based and DNA technologies, including ribozymes, ligation, and mRNA display, for clinical and research applications.
Collaborate with formulation, analytical, research, and GMP teams to pursue optimal mRNA designs and processes.
Analyze data and create graphs using appropriate software and data visualization tools.
Write reports describing results and methods, and present data at regular laboratory meetings.
Perform routine maintenance, operate, and manage inventory for laboratory instruments and reagents, including microplate readers, electrophoretic instrumentation, Tapestation, and centrifuges.
Follow proper safety recommendations and handling procedures for biological and chemical materials, and ensure others in the laboratory follow safety procedures.
Train other laboratory personnel as needed.
Perform other duties as assigned.