Senior Research Technician

Bexorg•New Haven, CT

7d•$39•Onsite

About The Position

Bexorg is seeking an experienced bench lead for day-to-day culture, assay, and imaging work on its NeuroScale team. The Senior Research Technician will independently run methods from start to finish, troubleshoot problems, write and maintain protocols, train junior technicians, and help improve and standardize laboratory methods as the team grows. The role is full-time and on-site in New Haven, Connecticut, and includes rotating night shifts. The technician will work closely with scientists and engineers, plan bench schedules, maintain instruments and accurate records, oversee data quality, prepare samples for external partners, and manage laboratory supplies, organization, and safety practices. The position reports to the Wet-Lab Lead, NeuroScale. Pay is listed as 38.50 plus a night-shift differential.

Requirements

Bachelor's degree in biology, neuroscience, biomedical engineering, or a related field; alternatively, an associate degree with equivalent hands-on experience.
At least 5 years of hands-on work as a research or laboratory technician in an academic, hospital, or industry lab; 7 or more years with an associate degree.
Demonstrated ability to independently run cell or tissue culture, fluorescence microscopy, qPCR, and at least one plate-based viability or metabolic assay such as CellTiter-Glo or lactate.
Hands-on cryosectioning of fixed or frozen tissue.
Experience writing SOPs and training others at the bench.
Willingness to work and lead rotating night shifts and weekends.
Comfort working with human post-mortem tissue under biosafety level 2 (BSL-2) practices.
Steady hands and close attention to detail when handling delicate tissue.
Careful and organized record keeping.
Ability to plan and prioritize work with minimal supervision and communicate clearly with scientists and engineers.
Can-do attitude.

Nice To Haves

RNAscope on tissue sections and multiplex immunofluorescence.
Organotypic slice culture, primary neural culture, or experience with human brain or other human tissue.
Drug screening and compound handling in 96- or 384-well formats, including liquid handlers.
Experience in an industry or regulated setting, such as GLP, using an electronic lab notebook (ELN) or laboratory information management system (LIMS).
Experience in a core facility, cell bank, or quality-control lab.
Basic image analysis using Fiji (ImageJ) or similar tools.

Responsibilities

Independently run and troubleshoot organotypic human brain slice culture, cell culture, multi-well drug screening, CellTiter-Glo, pyruvate and lactate assays, qPCR, RNAscope, cryosectioning, immunofluorescence staining, and fluorescence imaging.
Write, test, and maintain standard operating procedures for laboratory methods.
Plan the weekly bench schedule with scientists, including plate layouts, dosing schedules, assay time points, and imaging slots.
Lead rotating night shifts and respond to culture or equipment problems outside regular hours.
Train junior technicians, assess their skills in each method, and sign off when they are ready to work independently.
Ensure data quality by checking controls, flagging outliers and failed runs, and maintaining assay performance logs.
Maintain complete, accurate records of samples, treatments, and results in electronic lab notebooks and sample-tracking systems.
Maintain key instruments, perform routine care and calibration checks, and coordinate vendor service visits.
Work with the engineering team to improve and standardize laboratory methods and test changes at the bench.
Prepare and ship samples to outside partners using correct labels, dry-ice packing, and chain-of-custody records.
Manage laboratory stock and ordering, maintain lab organization, and follow safety practices for the team's work area.