Senior Research Scientist, Integrated Pharmacology (Contract)
About The Position
We seek a highly independent, collaborative and innovative scientist to join the Quantitative Cellular Pharmacology team in the Integrated Pharmacology group at Vertex Pharmaceuticals. The ideal candidate will be self-motivated with a strong foundation in cell biology and/or biochemistry and have experience with cell-based/biochemical assays. The successful candidate will be responsible for developing human disease-relevant assays to understand and address the underlying cause of serious life-threatening diseases. Our ideal candidate will have a track record of innovation in the field. The Integrated Pharmacology group supports late-stage drug discovery for all disease areas in the Vertex drug discovery portfolio at the Boston site and the Senior Research Scientist will be a member of multiple discovery project teams.
Requirements
- Strong understanding of Cell Biology and expertise in cell-based and/or biochemical assay development
- Target identification/validation, mechanism of action studies and understanding drug candidate pharmacology using innovative approaches and technologies is required
- Self-motivation, independence, organization, effective communication and presentation skills; adept in solving/troubleshooting complex problems as well as the ability to navigate a fast-paced work environment
- A desire to be part of a highly innovative company aimed at transforming the lives of people with serious diseases, their families and society
Nice To Haves
- Experience with miniaturized assays (384), knowledge of multiplex assay platforms, multi-parametric data analysis and basic command line programming is helpful
Responsibilities
- Lead the development of cell-based and/or biochemical assays for small molecule discovery as a key member of discovery project teams
- Execute cell based and/or biochemical assays supporting medicinal chemistry optimization, characterize our lead molecules in in vitro models of human disease and meet deliverables for preclinical development projects
- Analyze, critically interpret and present data to cross-functional project teams, and recommend courses of action based on datasets and discussions with biologists and chemists
- Propose and develop innovative approaches to small molecule discovery based on the latest technologies and publications in the field
- Identify and evaluate new technologies to improve efficiency and processes
- Be a key member of the Integrated Pharmacology group and serve as a strong representative on interdisciplinary project teams
- Ensure data integrity and compliance under Vertex policies
Benefits
- compensation, medical benefits, fringe benefits and other terms and conditions of employment shall be presented by the third-party agency partner upon offer.
Stand Out From the Crowd
Upload your resume and get instant feedback on how well it matches this job.
What This Job Offers
Job Type
Full-time
Career Level
Senior
Education Level
Ph.D. or professional degree
