Senior Research Associate
About The Position
Predicta is building a molecular insights platform for blood cancer care. From a single blood sample, the company generates longitudinal genomic and immune insights to help clinicians and researchers understand disease biology, guide treatment decisions, and monitor disease evolution. The Senior Research Associate will develop, optimize, and validate cell-based workflows that support clinical assays, with a focus on cell isolation and fluorescence-activated cell sorting (FACS). The role contributes to clinical testing quality and performance and to diagnostic work intended to improve patient outcomes. The position is located in Somerville, Massachusetts.
Requirements
- Bachelor’s or Master’s degree in Immunology, Molecular Biology, Biochemistry, or a related field.
- At least 3 years of hands-on flow cytometry/FACS experience, using a Sony MA900, BD Aria, or equivalent.
- Proficiency in multicolor (10–20+) flow cytometry panel design, compensation setup, and gating strategy development.
- Skill in data acquisition and analysis using FlowJo, Sony Cell Sorter software, or comparable tools.
- Experience participating in assay validations and implementing quality control measures.
- Demonstrated problem-solving and data-driven decision-making capabilities.
- Detail-oriented, with excellent organizational and documentation skills.
- Ability to adapt to a dynamic startup environment and manage multiple priorities.
Nice To Haves
- Significant experience with spectral flow sorters, such as Cytek Aurora or equivalent.
- Experience with molecular biology and/or next-generation sequencing (NGS) workflows in a research or clinical setting.
Responsibilities
- Perform and optimize multicolor flow cytometry staining and sorting of rare cell populations.
- Develop and refine antibody panels and gating strategies for cell subset identification and enrichment.
- Acquire, analyze, and document data using standard flow cytometry software.
- Establish and maintain best practices for instrument operation, maintenance, performance, and data reproducibility.
- Support flow-based validation studies under CLIA/CAP guidelines, ensuring traceability and documentation compliance.
- Process whole blood, bone marrow, PBMC, and BMMC samples for cell isolation, enrichment, and sorting.
- Support downstream workflows involving sorted material, including nucleic acid extraction and NGS library preparation or sequencing.
- Participate in cross-functional troubleshooting and optimization with clinical, R&D, and computational biology teams.
- Collaborate with clinical and R&D teams on technology transfer and testing execution.
- Assist in developing and refining laboratory procedures and workflows while maintaining complete and accurate records.
Benefits
- Equity.
- Flexible time off.
- 401(k) plan.
- Medical, dental, and vision coverage that is 90% paid by Predicta.
- Partially company-funded HSA.
- 10% bonus opportunity.
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What This Job Offers
Job Type
Full-time
Career Level
Senior
