Senior Research Associate

Takeda•Boston, MA

12d•$77,002 - $91,740•Hybrid

About The Position

Takeda Development Center Americas, Inc. is seeking a Senior Research Associate. This role involves executing routine experiments for analytical development, including sample preparation, equipment setup, and data acquisition according to SOPs. The associate will assist in planning basic experiments like Stress stability studies under supervisor guidance, documenting objectives, methods, and system suitability criteria. Responsibilities include interpreting results such as purity, assay performance, and trends with limited input, summarizing findings, and identifying deviations. The role requires operating and maintaining proficiency on instruments like HPLC/UPLC, GC-FID, UV-Vis, pH, and centrifugation, including calibration checks and basic maintenance. Maintaining high-quality lab notebook documentation consistent with GDP expectations, ensuring data integrity and traceability, and identifying, troubleshooting, and communicating routine technical issues are also key. Collaboration with departmental peers to coordinate workloads, share best practices, and deliver assignments on schedule, along with completing all required EHS compliance and role-specific training in a timely manner, are expected. Up to 20% remote work is allowed.

Requirements

Bachelor’s degree in Chemistry or related field
1 year of relevant work experience
Plan routine analytical experiments following technical protocols to quantify, analyze small molecules and large molecule compounds
Independently operate instruments (HPLC/UPLC) for analysis of samples
Prepare accurate pipetting and solution preparation (dilutions, concentrations)
Interpret results (e.g., purity, assay performance, trends) and communicate findings and out-of-spec observations
Perform chemical handling, labeling, segregation, spill response and proper disposal activities following lab safety procedures
Collaborate with cross-functional teams to test automation tools/workflows in the lab and provide user feedback

Responsibilities

Execute routine experiments to support analytical development including sample preparation, equipment setup, and acquire data per SOPs
Assist in planning basic experiments (e.g., Stress stability studies) with supervisor guidance, documenting objectives, methods and system suitability criteria
Interpret results (e.g. purity, assay performance, trends) with limited input
Summarize findings and identify deviations
Operate and maintain proficiency on instrument/operation (e.g., HPLC/UPLC, GC-FID, UV-Vis, pH, centrifugation), including calibration checks and basic maintenance
Maintain high-quality lab notebook documentation consistent with GDP expectations
Ensure date integrity and traceability
Identify, troubleshoot, and communicate routine technical issues (instrument errors, sample anomalies, out-of-spec observations) and escalate when needed
Collaborate with departmental peers to coordinate workloads, share best practices, and deliver assignments on schedule
Complete all required EHS compliance, and role-specific training in timely manner