Senior Research Associate - In Vitro Pharmacology & Biology

Novo Nordisk•Lexington, MA

2d•Onsite

About The Position

The Senior Research Associate will be responsible for strategy implementation and operations for conducting and summarizing non-clinical in vitro studies internally and externally in the support of new drug evaluations. Design, coordinate and report pre-clinical pharmacokinetic and pharmacodynamic in vitro experiments within research projects as part of target validation, target maturation, or mode-of-action studies. Develop and improve in vitro models supporting non-clinical studies, take an active role in research projects and contribute to innovation by identifying and exploring new therapeutic targets and principles. Communicate evaluations and implications of in vitro data internally, externally and in regulatory submissions as relevant. Demonstrates some subject matter knowledge. Sets and achieves day-to-day operations with some impact on others within or outside the unit. Works on problems of limited scope. Follows standard practices and procedures in analysing situations or data from which answers can be readily obtained. Normally receives general instructions on routine work and detailed instructions on new projects or assignments. Might require guidance from manager/senior colleagues. Hands-on work of increasing complexity; responsibility for experimental planning, execution & analyses with limited supervisor input; manages personal experimental timelines to meet deadlines for project with input from supervisor; may present ideas or data to team, site, or global project team; develops, optimizes & drafts protocols for methods of moderate complexity with reduced input from supervisor; contributes to formal study reports & study protocol drafting & review; may mentor junior staff.

Requirements

Bachelor’s or Master’s Degree in Cell and Molecular Biology, Biochemistry or Pharmaceutical Sciences preferred
3-5 years of relevant drug discovery laboratory experience in industrial or academic environment preferred
High School Diploma required with 10+ years’ relevant experience; or With an Associate or Vocational degree, 2+ years’ relevant experience required; BS/BA, 2+ years’ minimum relevant experience required; or Masters, with limited to no experience
Familiarity with pre-clinical pharmacokinetic and pharmacodynamic in vitro experiments
Knowledge of experimental design and in vitro model development
Strong understanding of drug discovery processes and target validation
Excellent scientific communication and stakeholder engagement skills

Responsibilities

Conduct and summarize non-clinical in vitro studies
Implement strategies and operations for conducting and summarizing non-clinical in vitro studies
Collaborate with internal and external stakeholders to support new drug evaluations
Ensure adherence to regulatory requirements and guidelines in conducting studies
Design and coordinate pre-clinical pharmacokinetic and pharmacodynamic experiments
Design experimental protocols for pre-clinical pharmacokinetic and pharmacodynamic studies
Coordinate the execution of in vitro experiments within research projects
Analyse and interpret data to draw conclusions and make recommendations
Develop and improve in vitro models supporting non-clinical studies
Identify opportunities to develop and enhance in vitro models for non-clinical studies
Conduct literature reviews and stay updated on the latest advancements in in vitro models
Collaborate with cross-functional teams to implement improvements and innovations in in vitro models
Communicate evaluations and implications of in vitro data
Prepare reports and presentations summarizing in vitro data and findings
Communicate the implications of in vitro data to internal stakeholders, external partners and regulatory authorities
Contribute to regulatory submissions by providing relevant in vitro data and analysis