Senior Research Associate, Immunology
About The Position
AskBio Inc., a subsidiary of Bayer AG, is a gene therapy company focused on developing life-saving medicines. The company has a portfolio of clinical programs for various diseases and utilizes proprietary technologies like Pro10™ for manufacturing. With global headquarters in Research Triangle Park, North Carolina, and European headquarters in Edinburgh, Scotland, AskBio is dedicated to pioneering science to create transformative molecular medicines. The Senior Research Associate, Immunology will play a key role in understanding AAV Immunogenicity by performing analyses on clinical study samples using immunological assays. This role involves assay development, validation, real-time immune assessments, and clinical sample coordination. It offers an opportunity to build expertise in Cell Biology and Immunology, contributing to the advancement of gene therapy clinical programs. The position reports to the Senior Director of Immunology and is a full-time, on-site role in Philadelphia, PA.
Requirements
- Bachelor’s degree in a related field with 5+ years of experience; or Master’s degree in a related field with 2+ years of experience; or High School Diploma with 9+ years of experience
- Advanced lab skills in cell biology, cell culture, immunology, reagent preparation, and adherence to biosafety and chemical use guidelines
- Familiarity with handling and working with human clinical lab samples
- Familiarity with GCP/GLP/GxP lab standards and practices
- Flexible schedule to accommodate real-time and urgent sample analysis; May include weekend, holiday and after-hours availability
- Advanced office skills using a PC and working with MS office tools (Word, Excel and PowerPoint)
- Must be self-motivated, organized, capable of working independently as well as a team contributor
- Strong oral and written communication skills, particularly in writing technical documents such as SOPs, assay validation plans, reports and clinical sample testing plans and reports
- Excellent interpersonal skills with the ability to interact effectively with teams, internally and externally
- Ability to work independently with minimal supervision under direct/remote management but also work collaboratively with a broader team and across functional departments
Nice To Haves
- Experience in immunoassays such as ELISA, ELISPOT/FluoroSpot, neutralizing antibody, MSD, cytokine release and flow cytometry
- Previous experience with handling clinical lab samples and blood processing workflow
- Experience with LIMS systems (e.g. LabVantage)
- Familiarity with statistical analysis
Responsibilities
- Performance of complex assays without supervision
- Perform assay development of new clinical assays which may include the optimization, qualification, validation, and troubleshooting of new analytical methods
- Perform data analysis and interpret the results accurately
- Preparation of validation reports and summaries
- Coordinate with Clinical team and/or Immunology lab manager for sample receiving and testing
- Participate in team and clinical program meetings as needed to report results, discuss data and address program needs
- Build and maintain a compliant GxP lab environment and adhere to GLP/GcLP guidelines
- Author standard operating procedures (SOPs) for new assay protocols and use of new laboratory equipment
- Maintain a laboratory notebook or binder with worksheets recording details of performed experiments according to good documentation practices
- Train and mentor Research Associates, contractors, and junior members of the laboratory
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What This Job Offers
Job Type
Full-time
Career Level
Senior
Education Level
High school or GED
