Research Associate, Tuberculosis Genetics and Immunology

UT Southwestern Medical Center • Dallas, TX

4d • Onsite

About The Position

We are seeking a highly motivated Research Associate to join our research team investigating the genetic and immunological basis of susceptibility to tuberculosis (TB). This position will support ongoing multidisciplinary research projects and ensure continuity within the laboratory. The successful candidate will contribute to projects aimed at identifying the molecular and cellular mechanisms underlying human susceptibility to Mycobacterium tuberculosis infection. The candidate will perform a broad range of experimental procedures spanning molecular genetics, cellular immunology, and deep immunophenotyping. Responsibilities will include nucleic acid extraction, PCR-based assays, genotyping, cell isolation and culture, functional immune assays, sample processing, data acquisition, and meticulous record keeping. The position also involves assisting with protocol optimization, maintaining laboratory organization, and ensuring compliance with biosafety and quality standards. Experience with flow cytometry is highly desirable, including sample preparation, antibody staining, instrument operation, and data analysis. Familiarity with high-dimensional or spectral flow cytometry is an advantage but is not required. Additional experience with molecular biology techniques, cell culture, and immune-based assays will be considered favorably. This position offers the opportunity to contribute to cutting-edge research aimed at understanding the genetic and immunological determinants of tuberculosis susceptibility, with the ultimate goal of improving diagnosis, prevention, and treatment of this major global infectious disease.

Requirements

• Master's Degree with major coursework in field of assignment OR Bachelor's Degree with major coursework in field of assignment
• 3 years of laboratory experience with Master's degree including 2 years at level of Research Assistant II or equivalent
• 4 years of laboratory experience with Bachelor's degree including 2 years at level of Research Assistant II or equivalent.

Nice To Haves

• Degree in biology, immunology, microbiology, molecular biology, or a related field.
• Experience with molecular biology techniques and cell-based assays.
• Experience with flow cytometry is strongly preferred.
• Experience with high-dimensional or spectral flow cytometry.
• Excellent organizational skills, attention to detail, and the ability to maintain accurate experimental records.
• Ability to work both independently and collaboratively in a multidisciplinary research environment.
• Strong communication skills and enthusiasm for translational infectious disease research.

Responsibilities

• Perform nucleic acid extraction, PCR-based assays, and genotyping.
• Conduct cell isolation and culture, and functional immune assays.
• Process samples and acquire data.
• Maintain meticulous record keeping.
• Assist with protocol optimization.
• Maintain laboratory organization.
• Ensure compliance with biosafety and quality standards.
• Recommends and/or initiates new or modified procedures and techniques based upon latest developments in assigned field or analysis of research data.
• Performs computer programming for accumulation and analysis of research data.
• Designs, constructs, repairs, or modifies electronic and/or mechanical equipment or apparatus used in experiments and research projects.
• Instructs medical students, graduate students, residents, or other laboratory personnel of lower grade with respect to techniques, procedures, and equipment utilized in research or experiments.
• Assists principal investigator and other professional personnel in writing of reports and papers for publication.
• May provide working supervision to employees of lower grade engaged in performance of variety of difficult and complex laboratory work tasks.
• Performs other duties as assigned.

Benefits

• PPO medical plan, available day one at no cost for full-time employee-only coverage
• 100% coverage for preventive healthcare-no copay
• Paid Time Off, available day one
• Retirement Programs through the Teacher Retirement System of Texas (TRS)
• Paid Parental Leave Benefit
• Wellness programs
• Tuition Reimbursement
• Public Service Loan Forgiveness (PSLF) Qualified Employer

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level