Senior Research Associate, Histology
Flagship Pioneering, Inc.•Cambridge, MA
•$81,000 - $107,250•Onsite
About The Position
Serif Biomedicines is seeking an experienced Sr. Research Associate to lead histology and related bio-analytics for platform development and therapeutic proof-of-principle. This role involves working with animal models and requires scientific rigor, intellectual curiosity, enthusiasm, and a desire to innovate new nucleic acid therapeutics. The individual will operate in a dynamic, fast-paced entrepreneurial environment, working both independently and as part of a highly collaborative and rapidly growing team.
Requirements
- Masters or BS in relevant discipline with 5+ years of industry experience.
- Experience with in-vivo studies, ideally involving LNP delivery and/or nucleic-acid based therapeutics in rat, mouse, and NHP.
- Deep expertise in ex-vivo analytical assays such as ELISA, MSD, qPCR, ddPCR, FACS, etc.
- Experience with histological tissue analysis (IHC/IF, ISH, H&E, etc.) including tissue harvest, embedding, sectioning, staining, imaging and image analysis.
- Strong communication and interpersonal skills.
- Strong organizational, analytical, and problem-solving skills.
- Ability to thrive in a fast-paced, multidisciplinary, and rapidly growing biotech environment.
Nice To Haves
- Experience with various mouse and rat models of diseases is a plus.
- Experience performing in-vivo procedures in rodents, including preparation and administration of therapeutics and collecting material (blood, tissue, etc.) for ex-vivo analysis is a plus.
- Hands-on experience with flow-cytometry, including panel design, execution and analysis is a plus.
Responsibilities
- Execution and analysis of bio-analytics, including histology, to assess efficacy, safety and biodistribution of novel nucleic acid therapeutics.
- Provide scientific and technical perspectives to advance platform development.
- Develop in-house capabilities to support work performed at CROs.
- Effectively communicate experimental findings in oral, written, and visual formats.
- Work independently and collaboratively in a multidisciplinary team environment.
- Demonstrate flexibility in supporting the accelerated timelines associated with data generation, analysis, and reporting for in vivo studies.
Benefits
- healthcare coverage
- annual incentive program
- retirement benefits
- a broad range of other benefits
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What This Job Offers
Job Type
Full-time
Career Level
Senior
