Senior Research Associate, Histology

Serif Biomedicines, Inc.Cambridge, MA
$81,000 - $107,250

About The Position

Serif Biomedicines is seeking an experienced Sr. Research Associate to lead histology and related bio-analytics for platform development and therapeutic proof-of-principle. This role involves working with animal models and requires scientific rigor, intellectual curiosity, enthusiasm, and a desire to innovate new nucleic acid therapeutics. The individual will operate in a dynamic, fast-paced entrepreneurial environment, working both independently and as part of a highly collaborative and rapidly growing team.

Requirements

  • Masters or BS in relevant discipline with 5+ years of industry experience.
  • Experience with in-vivo studies, ideally involving LNP delivery and/or nucleic-acid based therapeutics in rat, mouse, and NHP.
  • Deep expertise in ex-vivo analytical assays such as ELISA, MSD, qPCR, ddPCR, FACS, etc.
  • Experience with histological tissue analysis (IHC/IF, ISH, H&E, etc.) including tissue harvest, embedding, sectioning, staining, imaging and image analysis.
  • Strong communication and interpersonal skills.
  • Strong organizational, analytical, and problem-solving skills.
  • Ability to thrive in a fast-paced, multidisciplinary, and rapidly growing biotech environment.

Nice To Haves

  • Experience with various mouse and rat models of diseases is a plus.
  • Experience performing in-vivo procedures in rodents, including preparation and administration of therapeutics and collecting material (blood, tissue, etc.) for ex-vivo analysis is a plus.
  • Hands-on experience with flow-cytometry, including panel design, execution and analysis is a plus.

Responsibilities

  • Execution and analysis of bio-analytics, including histology, to assess efficacy, safety and biodistribution of novel nucleic acid therapeutics.
  • Provide scientific and technical perspectives to advance platform development.
  • Develop in-house capabilities to support work performed at CROs.
  • Effectively communicate experimental findings in oral, written, and visual formats.
  • Work independently and collaboratively in a multidisciplinary team environment.
  • Demonstrate flexibility in supporting the accelerated timelines associated with data generation, analysis, and reporting for in vivo studies.

Benefits

  • healthcare coverage
  • annual incentive program
  • retirement benefits
  • a broad range of other benefits
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