Senior Product Manager

Caris Life Sciences•Irving, TX

3d•Hybrid

About The Position

Caris Life Sciences is a global leader in precision oncology, utilizing advanced molecular science and AI to transform cancer care and improve patient lives. The company is seeking a Senior Product Manager to own the end-to-end lifecycle of clinical software products. This role involves driving product strategy, roadmap development, and execution for critical software solutions that support laboratory operations, clinical decision-making, and patient reporting. The position offers the opportunity to work with cutting-edge technology, including AI-powered tools, and to contribute to a mission-driven organization focused on improving healthcare outcomes. The role is based in Irving, Texas, with a hybrid work model, co-located with Caris's laboratory and clinical operations.

Requirements

Bachelor's degree in Business, Computer Science, Engineering, Health Informatics, or a related field, or equivalent practical experience.
8+ years in product management, or equivalent product or program leadership, including ownership of technical or platform-scoped work.
End-to-end ownership of a live software product, from strategy and roadmap through delivery and post-release outcomes.
A track record of writing structured product requirements (epics, user stories, acceptance criteria) that engineering teams built and shipped.
Experience defining and tracking adoption, utilization, or outcome measures and using them to drive product decisions.
Experience facilitating alignment across clinical, operational, commercial, and technical stakeholders.
Fluency with generative AI tools in product discovery, analysis, requirements, or documentation work.

Nice To Haves

Advanced degree, such as an MBA, in a relevant field.
Experience in healthcare diagnostics, molecular pathology, clinical laboratory, or life sciences software.
Experience in environments governed by FDA, SOX, CLIA, or HIPAA requirements.
Ability to translate regulatory or compliance constraints into actionable product requirements.
Experience taking a new product or major product line from concept through launch and early adoption.
Familiarity with agile delivery frameworks and associated product-management tooling.
Strong written and verbal communication skills with stakeholders at varying levels of technical and clinical fluency.

Responsibilities

Own strategy and a rolling roadmap for an assigned clinical software product, turning company priorities and stakeholder evidence into a sequenced, value-ordered backlog.
Drive continuous discovery with ordering physicians, pathologists, geneticists, laboratory operations, and commercial teams who use and depend on the product; validate problems before they become roadmap commitments.
Write product requirements engineering teams can move on: epics, user stories, and acceptance criteria clear enough to build from and complete enough for a regulated environment.
Own release definition: scope the minimum viable release, set launch-readiness criteria, and make the go/no-go call with engineering, quality, and regulatory partners.
Own what happens after launch: define adoption, utilization, and outcome measures; partner with engineering to instrument them; and iterate or retire capabilities on the evidence.
Run the working sessions that keep clinical, operational, commercial, and technical stakeholders aligned, making trade-offs visible and priority calls defensible.
Make the case for investment: put the clinical, operational, and business impact of proposed features, technical-debt work, and regulatory change in terms leadership can act on.
Build SOX and FDA change-control obligations into product plans from the start, working with quality and regulatory teams so compliance moves at the pace of delivery.
Use generative AI as daily leverage in discovery synthesis, analysis, requirements drafting, and product documentation.
Prioritize automation of recurring manual steps in the product's operational workflows, and count the manual touches removed as a product outcome.