Senior Principal Statistician

Johnson & Johnson Innovative Medicine • Spring House, PA

7d • Hybrid

About The Position

We are seeking an outstanding Senior Principal Statistician to join our Discovery Oncology Statistics organization within Johnson & Johnson Innovative Medicine Research & Development. This scientific leadership role provides strategic statistical leadership across oncology drug discovery programs, representing statistics in key scientific and portfolio discussions and helping drive critical decisions from target identification through candidate selection and translational biomarker development. This is an exciting opportunity to influence the future of cancer drug discovery by applying innovative statistical methodologies, machine learning, data science, and quantitative decision-making to some of the most exciting scientific questions in oncology. The successful candidate will collaborate across multidisciplinary research teams and contribute to innovation that directly impacts the advancement of transformational medicines for patients.

Requirements

• Minimum of a PhD in Statistics, Biostatistics, Applied Statistics, Bioinformatics, Data Science, or a related quantitative discipline with a minimum of 6 years of relevant experience in pharmaceutical, biotechnology, or healthcare research is required.
• Recognized expertise in statistical methods, experimental design, and quantitative decision-making for drug discovery and translational research.
• Track record of influencing scientific and portfolio decisions through quantitative evidence.
• Experience applying modeling, simulation, predictive analytics, and high-dimensional data analysis.
• Ability to translate statistical concepts into actionable insights for scientific and business audiences.
• Scientific leadership of complex programs, shaping scientific strategy and decision-making across multidisciplinary teams.
• Proficiency in R and modern computational and AI-enabled workflows.

Nice To Haves

• Recognized expertise in oncology drug discovery, translational research, and biomarker-driven decision-making.
• Experience applying machine learning, artificial intelligence, and advanced analytical methods to biomedical and drug discovery datasets.
• Experience with genomic, transcriptomic, proteomic, imaging, spatial biology, or other multi-omics datasets.
• Previous people leadership, mentoring, scientific coaching, or matrix leadership experience.
• Experience leading external collaborations, academic partnerships, scientific consortia, or industry working groups, with a demonstrated record of external scientific impact.

Responsibilities

• Lead statistical strategy for priority oncology programs and shape scientific and portfolio decisions through quantitative evidence.
• Apply and advance statistical modeling, AI/ML, biomarker analytics, and quantitative decision frameworks to accelerate drug discovery.
• Drive experimental design, modeling, and data analysis across translational, in vivo, combination, and high-dimensional studies.
• Forge partnerships across functions and external organizations to advance program objectives and quantitative decision-making.
• Develop analytics capabilities, AI-enabled workflows, statistical methods, and decision-support tools with data science partners.
• Champion reproducible research, data integrity, statistical standards, and methodological rigor.
• Lead publications, scientific presentations, and external collaborations that advance statistical methods and scientific practice.

Benefits

• Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act. Johnson & Johnson is committed to providing an interview process that is inclusive of our applicants’ needs. If you are an individual with a disability and would like to request an accommodation, external applicants please contact us via https://www.jnj.com/contact-us/careers, internal employees contact AskGS to be directed to your accommodation resource.

What This Job Offers

• Job Type: Full-time
• Career Level: Senior
• Education Level: Ph.D. or professional degree