Senior Organic Chemist

Adiabatic Materials•Somerville, MA

3d•$110,000 - $170,000•Onsite

About The Position

We have built a novel and differentiated chemistry platform and are seeking a Senior Organic Chemist to expand its capabilities and demonstrate its value on real pharmaceutical and fine chemical targets. Working closely with our Chief Scientific Officer, you will identify and validate new reaction classes, devise routes that take advantage of our chemistry, and turn those ideas into robust experimental results. You will own the synthesis end-to-end, including designing and running reactions, developing and optimizing new transformations, and rapidly purifying, characterizing, and reporting products. Electrochemistry experience is not required, as we can get an excellent synthetic chemist up to speed on our system quickly. What matters most is strong synthetic intuition, speed at the bench, and the ability to take a target from route concept through validated chemistry.

Requirements

PhD in chemistry or a closely related field with a research focus in organic synthesis: new reactions, condition optimization, novel compounds
Deep and diverse hands-on experience across many reaction types
Standard air-free technique on a Schlenk line, in vials and flasks
Independent purification by column chromatography and characterization by NMR, IR, MS, UV-Vis, HPLC and GC (some hands-on, some via analytical labs)

Nice To Haves

2-4 years of industry or startup experience
Retrosynthetic analysis
Cheminformatics or computational chemistry
Electrochemistry experience (will be learned on the job)

Responsibilities

Take high-level direction, then develop and run whole synthetic routes independently: read the procedure, execute it correctly, adapt it where it doesn’t transfer, and deliver assigned targets.
Develop and optimize conditions for reaction types beyond our current set, including those requiring standard air-free technique.
Learn the cell and mediator chemistry hands-on with our Director of Electrochemical Engineering, run the electrochemical step as one step among multiple, and help expand the reaction scope.
Purify and characterize independently and quickly, and set a documentation and reporting standard the growing R&D team can follow.
Work within the Greentown Labs safety environment from day one and run hazard assessments for every new reaction type you introduce.
Contribute in R&D meetings, work with our scientific advisors on open chemistry questions, and mentor our chemistry co-op informally on technique.