About The Position

The Core Transformation Management Office (TMO) within McKesson’s Medical‑Surgical business is seeking a Senior Manager to play a critical role in driving enterprise transformation initiatives with significant financial and organizational impact. This role is a high‑impact, highly visible opportunity to help shape and deliver enterprise transformation across the Medical‑Surgical business. This role sits at the center of some of the most critical initiatives underway—spanning operational transformation and business separation efforts—representing over $200 million in profit impact in the current fiscal year. This role is part of a newly formed, strategically critical organization built to drive execution rigor, transparency, and value realization across the enterprise. The Senior Manager will work alongside three to four Portfolio Managers, collectively overseeing a transformation portfolio of approximately 35 concurrent initiatives. Success in this role directly influences leadership’s ability to make informed decisions, sequence work effectively, and deploy resources where they deliver the greatest return. Designed as a senior individual‑contributor role, this position is ideal for an analytically strong, execution‑oriented leader who thrives in complexity, operates comfortably with senior executives, and brings clarity to ambiguous, fast‑moving environments. The Senior Manager serves as a portfolio‑level execution and analytics leader, partnering closely with Portfolio Managers, FP&A, and senior leaders across the organization. While the role may resemble project management at a glance, its scope is far more strategic—focused on portfolio management, capacity planning, prioritization, and executive decision readiness. The role ensures leaders have a clear, data‑backed view of what is happening across the transformation portfolio, where constraints and risks exist, and what decisions are required to keep initiatives on track.

Requirements

  • Typically requires 10+ years of relevant experience. Less years required if has relevant Master’s or Doctorate qualifications
  • 10 years of experience in transformation, strategy, finance, operations, consulting, or program leadership
  • Strong financial acumen with experience in business cases, performance metrics, and value tracking
  • Proven ability to operate effectively in matrixed environments and influence without direct authority
  • Exceptional analytical, synthesis, and executive communication skills
  • Highly organized, proactive, and comfortable navigating ambiguity

Responsibilities

  • Identify capacity constraints across people, IT, and shared enterprise resources.
  • Surface conflicts where multiple initiatives compete for the same resources.
  • Proactively elevate risks and trade‑offs to senior leadership, enabling early, informed intervention.
  • Evaluate initiatives based on effort, return, feasibility, and timing.
  • Own and maintain prioritization matrices that distinguish high‑effort vs. high‑return work.
  • Support leadership decisions on whether initiatives should advance, pause, be re-sequenced, or be reconsidered altogether.
  • Compile, analyze, and synthesize complex data into clear, executive‑ready insights.
  • Build and reassess analytics behind business cases as assumptions evolve.
  • Ensure leaders have transparent, reliable information to support difficult trade‑off decisions and portfolio rebalancing.
  • Work directly with senior leaders and their teams to frame issues, clarify implications, and enable decisive action.
  • Translate complex data into clear narratives that drive alignment and momentum.
  • Influence outcomes without direct authority by bringing structure, credibility, and insight to executive conversations.
  • Support both the transformation of how the business operates and the work required to separate the business.
  • Navigate the intersection of these efforts, where competing priorities often collide.
  • Drive proactive planning, sequencing, and escalation to ensure progress despite overlapping demands.

Benefits

  • 16 Days PTO
  • 12 Paid Holidays (includes 5 personal holidays)
  • Company Matched 401K
  • Health Benefits beginning the month after you start
  • Tuition Reimbursement
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