Senior Manager, Ontology

Takeda•Boston, MA

2d•$137,000 - $215,270•Hybrid

About The Position

As a Senior Manager, Ontology, you will be a hands-on R&D BioPharm data curator responsible for harmonizing Research, Development, and Global Medical data into standardized, analysis-ready, FAIR-aligned datasets. You will partner up with data owners/stewards and data platform teams to operationalize metadata standards, ontology/terminology mapping, versioning, and QC—improving throughput through scalable processes and targeted automation.

Requirements

Bachelor’s degree with relevant experience or advanced degree (MS/PhD) in life sciences, bioinformatics, data science, or related field.
4–7+ years in biomedical data curation/harmonization, data management/modeling, and/or data governance (pharma/biotech/CRO/vendor).
Experience mapping to controlled vocabularies/ontologies (e.g., NCIT, MedDRA, BAO, CL, CHEBI, Allotrope, PROCO or similar).
Experience with ontology management tools (e.g., SciBite CENtree, TopBraid Composer, or equivalent).
Experience defining/executing QC/QA checks and maintaining SOPs.
Version control experience; ability to track and merge ontology changes.

Nice To Haves

Experience partnering with data platform/engineering teams to implement validation/QC/ingestion workflows.
Familiarity with W3C semantic web/ontology standards (RDF/RDFS/OWL/SKOS/SHACL).

Responsibilities

Curate and harmonize biomedical datasets; ensure completeness, consistency, traceability, and audit readiness using ontology tools and tabular workflows.
Partner with data owners/stewards to collect required artifacts and build metadata using templates and tooling.
Map entities to controlled vocabularies/ontologies; manage terminology decisions, documentation, and versioning.
Maintain application and domain ontologies across environments; follow data exchange processes and define contextual rules to support orchestration, discoverability and reuse.
Define and execute QC/QA standards, SOPs, and governance practices; produce QC outputs and release documentation.
Lead cross-functional delivery and stakeholder communication: curation decisions, risks, and tradeoffs.
Identify and implement workflow improvements, including automation, and contribute to onboarding and best practices for the ontology tool suite.
Facilitate working sessions and training with stewards/SMEs to resolve definition conflicts and mapping edge cases.