Senior Manager, Ontology
Takeda•Boston, MA
•Hybrid
About The Position
As a Senior Manager, Ontology, you will be a hands-on R&D BioPharm data curator responsible for harmonizing Research, Development, and Global Medical data into standardized, analysis-ready, FAIR-aligned datasets. You will partner up with data owners/stewards and data platform teams to operationalize metadata standards, ontology/terminology mapping, versioning, and QC—improving throughput through scalable processes and targeted automation.
Requirements
- Bachelor’s degree with relevant experience or advanced degree (MS/PhD) in life sciences, bioinformatics, data science, or related field.
- 4–7+ years in biomedical data curation/harmonization, data management/modeling, and/or data governance (pharma/biotech/CRO/vendor).
- Experience mapping to controlled vocabularies/ontologies (e.g., NCIT, MedDRA, BAO, CL, CHEBI, Allotrope, PROCO or similar).
- Experience with ontology management tools (e.g., SciBite CENtree, TopBraid Composer, or equivalent).
- Experience defining/executing QC/QA checks and maintaining SOPs.
- Version control experience; ability to track and merge ontology changes.
Nice To Haves
- Experience partnering with data platform/engineering teams to implement validation/QC/ingestion workflows.
- Familiarity with W3C semantic web/ontology standards (RDF/RDFS/OWL/SKOS/SHACL).
Responsibilities
- Curate and harmonize biomedical datasets; ensure completeness, consistency, traceability, and audit readiness using ontology tools and tabular workflows.
- Partner with data owners/stewards to collect required artifacts and build metadata using templates and tooling.
- Map entities to controlled vocabularies/ontologies; manage terminology decisions, documentation, and versioning.
- Maintain application and domain ontologies across environments; follow data exchange processes and define contextual rules to support orchestration, discoverability and reuse.
- Define and execute QC/QA standards, SOPs, and governance practices; produce QC outputs and release documentation.
- Lead cross-functional delivery and stakeholder communication: curation decisions, risks, and tradeoffs.
- Identify and implement workflow improvements, including automation, and contribute to onboarding and best practices for the ontology tool suite.
- Facilitate working sessions and training with stewards/SMEs to resolve definition conflicts and mapping edge cases.
Benefits
- medical, dental, vision insurance
- a 401(k) plan and company match
- short-term and long-term disability coverage
- basic life insurance
- a tuition reimbursement program
- paid volunteer time off
- company holidays
- well-being benefits
- up to 80 hours of sick time per calendar year
- up to 120 hours of paid vacation for new hires
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What This Job Offers
Job Type
Full-time
Career Level
Senior
