Senior Manager, Clinical Site Payments, Portfolio Management

BeiGene

17d•$136,400 - $181,400•Onsite

About The Position

The Senior Manager, Clinical Site Payment Portfolio Management is responsible for global financial oversight, reconciliation, and portfolio-level governance of investigator grant payments across BeOne-sponsored clinical trials. This role partners closely with the Director of Clinical Site Payments, Head of CBO, Regional Clinical Site Payments teams, R&D Finance, Global R&D Sourcing (GRDS), payment vendors, and cross-functional stakeholders to ensure accurate financial reporting, accrual integrity, and compliance with SOX and internal control frameworks. This position serves as a critical interface between Clinical Operations and Finance, responsible for end-to-end management of investigator grant financials, including monthly reconciliation, accrual accuracy, Budget vs. Actuals (BvA) tracking, and forward-looking financial forecasts. The role also owns Clinical Site Payment portfolio metrics, reporting, and analytics dashboards, and ensures alignment of payments data with approved budgets, negotiated contracts, and the Clinical Payment taxonomy (CPT codes, CTP categories, subcategories) in accordance with the CPP Library framework.

Requirements

Advanced knowledge Microsoft Office - Word, Excel, Power Point and MS Outlook; Smartsheet, SharePoint, MS Teams
Fluent in both written and verbal English.
Strong proficiency in Excel, financial systems (SAP, Oracle, Ariba, Agiloft) and vendor clinical payment platforms, with the ability to manipulate and interpret key financial data effectively
Exceptional accuracy and attention to detail.
Proven ability to prioritize workload and manage multiple tight deadlines effectively in a fast-paced environment.
Strong interpersonal skills, with demonstrated leadership, negotiation, analytical, and problem-solving abilities.
Capable of multitasking and meeting compressed timelines.
Ability to set priorities while managing multiple demands simultaneously.
Critical thinker with a proactive approach to problem-solving.
Self-starter with the flexibility to work independently while exercising sound judgment and initiative.
Prior experience in clinical trial finance, clinical site budgeting, vendor sourcing, clinical operations, clinical payments, finance, and/or accounting.
Proven ability to build and maintain financial models
Cash flow forecasting and accrual projections
Background in clinical and drug development within the biotech/pharmaceutical industry.
Experience in clinical business operations, business process management, and project management.
Strong understanding of SOX compliance and financial control frameworks
Experience supporting financial close processes and audit readiness
High attention to detail with strong focus on accuracy, documentation, and auditability
Bachelor’s degree from an Accredited College, and at least 7+ years’ experience in finance, biotech, pharmaceuticals, or a related field in the biotech/pharmaceutical industry

Nice To Haves

Fosters Teamwork
Provides and Solicits Honest and Actionable Feedback
Self-Awareness
Acts Inclusively
Demonstrates Initiative
Entrepreneurial Mindset
Continuous Learning
Embraces Change
Results-Oriented
Analytical Thinking/Data Analysis
Financial Excellence
Communicates with Clarity

Responsibilities

Lead monthly reconciliation of global investigator grant expenses, ensuring alignment across site payments, vendor disbursements, and financial ledgers
Review and validate payment vendor drawdowns, ensuring appropriate funding levels and supporting documentation
Partner with Regional Clinical Site Payments teams and vendors to investigate discrepancies and drive timely resolution
Maintain a consolidated portfolio view of payments, accruals, commitments, and outstanding liabilities
Oversee creation, maintenance, and lifecycle management of Purchase Requisitions (PRs) and Purchase Orders (POs) for clinical site payments and vendors
Ensure POs accurately reflect study budgets, amendments, and forecasted spend
Monitor PO balances, utilization, and close-out activities to support financial accuracy and audit readiness
Manage vendor invoice review, validation, and approvals in collaboration with GRDS and R&D Finance
Own monthly PO accrual analysis and reporting in partnership with R&D Finance and GRDS
Ensure accurate and timely investigator grant accruals in compliance with financial close timelines and SOX requirements
Perform Budget vs. Actuals analysis at study and portfolio level, identifying key variances, trends, and financial risks
Partner with R&D Finance and Treasury to support financial close activities and ensure completeness of recorded expenses
Develop deep understanding of site-level financial closeout processes to ensure completeness of final investigator grant expenses
Partner with GRDS and R&D Finance to identify and project outstanding expenses incurred but not yet invoiced by sites
Ensure accrual coverage for unbilled costs through closeout periods and study transitions
Support accurate financial representation of liabilities across the clinical portfolio
Develop and maintain financial models to support accrual forecasting and cash flow projections, scenario analysis, and internalization strategies for clinical payments
Lead short-term and long-term forecasting for internalized countries in partnership with R&D Finance and Treasury
Analyze impact of business and operational changes on financial performance and portfolio risk
Own Clinical Site Payment KPIs, metrics framework, and reporting cadence
Develop and maintain analytics dashboards (e.g., Power BI) to monitor payment cycle times, accrual vs. actual accuracy, forecast deviations, and vendor performance and financial trends
Partner with CBO Budget Planning & Strategy, Clinical Site Contracts, and Clinical Site Data Hub to ensure payments are aligned with approved budgets and negotiated contract terms, payment data is accurately mapped to CPT codes, categories, and subcategories, and consistency with the CPP Library data structure across reporting systems
Drive data integrity, standardization, and alignment across systems and stakeholders
Act as primary liaison between Clinical Site Payments, R&D Finance, and Treasury for investigator grant financial management
Collaborate with Global Clinical Operations and R&D Finance on budget assumptions and financial tracking methodologies
Support strategic initiatives and project execution, including payment internalization and process optimization
Ensure adherence to SOX requirements and internal financial control frameworks
Maintain audit-ready documentation for payments, accruals, reconciliations, and PO lifecycle management
Lead quarterly external audit preparation by partnering with Regional Clinical Site Payments teams to compile and validate audit samples
Coordinate with BeOne Controller and R&D Finance to support audit reviews and inquiries
Identify control gaps and drive continuous improvements to strengthen financial governance