Senior Manager, Clinical Operations
About The Position
Iterative Health is a healthcare technology and services company powering the acceleration of clinical research to transform patient outcomes. We built a leading performance-driven network of 100+ sites across the US, Europe, India, and Australia, conducting research directly in the communities where care is delivered across gastrointestinal, hepatology, obesity, and cardiology. By combining deep clinical trial expertise with cutting-edge AI, we connect sponsors' scientific ambitions with high-performing research teams that expedite and expand access to novel therapeutics for patients in need. Today, Iterative Health is headquartered in Cambridge, Massachusetts, and New York City with 250+ employees world-wide. At Iterative Health, we are transforming clinical research through the power of AI, technology, and human expertise. Iterative Health is a healthcare technology and services company powering the acceleration of clinical research to improve patient outcomes. Through the Iterative Health Site Network — a premier network of 100+ clinical research sites across the US and Europe — we help expand and expedite access to novel therapeutics for patients in need.
Requirements
- Bachelor's degree or equivalent combination of education and experience.
- 8+ years of experience supporting Phase II-IV sponsor-funded clinical trials.
- Deep understanding of clinical trial operations, including study startup, feasibility, regulatory processes, protocol execution, and GCP requirements.
- Experience working directly with sponsors, CROs, investigative sites, and cross-functional stakeholders.
- Demonstrated ability to manage multiple priorities, navigate ambiguity, and drive projects to successful completion.
- Strong analytical, communication, and stakeholder management skills.
- Comfort adopting and leveraging new technologies and operational tools.
- Willingness to travel up to 30%.
Nice To Haves
- Experience in GI clinical research
- Prior project or program management experience.
- 5+ years of experience as a Clinical Research Associate (CRA) , or 3+ years leading clinical operations teams.
- Experience working in a high-growth or startup environment.
- Experience presenting to sponsors, CRO leadership, and executive stakeholders.
Responsibilities
- Own the end-to-end site activations, managing timelines, dependencies, and risks across multiple concurrent sites and trials
- Help teams prioritize tasks and ensure milestones are met within defined SLAs
- Maintain activation plans, status tracking, and documentation, escalating risks and delays proactively
- Serve as the primary operational partner to sponsors, CROs, and sites throughout the trial lifecycle.
- Lead and support sponsor, CRO, and partner meetings by providing clinical operations expertise, actionable insights, and strategic recommendations.
- Build strong relationships with key stakeholders and ensure alignment on study goals, performance metrics, and operational priorities.
- Proactively communicate study risks, mitigation plans, and escalation strategies.
- Facilitate educational sessions, webinars, and customer forums to strengthen engagement and share best practices.
- Travel as needed to customer sites, investigator meetings, conferences, and sponsor engagements (up to 30%).
- Monitor study performance metrics and own activation-specific reporting, including time-to-activation, SLA performance, and root causes of delays
- Analyze and provide feedback to sponsor/CRO on slower-than-expected enrollment, high screen fail rates, and/or variability in site performance
- Use data to inform prioritization and process improvements
- Identify operational gaps affecting site activation, enrollment, and execution, and collaborate cross-functionally to address them
- Advocate for site needs and serve as a subject matter expert in clinical research operations
- Collaborate cross-functionally to implement solutions that improve site performance and study outcomes.
- Partner with sponsors and CROs to streamline processes and optimize site activation timelines.
- Performs related duties as requested
Benefits
- Hybrid work environment with in-office collaboration two days per week in either our NYC or Boston office
- Comprehensive medical, dental, and vision coverage, with up to 80% of premiums covered by Iterative Health
- Mental health and wellness support through Spring Health
- Health HSA or FSA options, and commuter FSA contributions supported by Iterative Health
- Unlimited PTO, 12 company holidays, and a company-wide shutdown between Christmas and New Years
- 401(k) program with a company match of up to 3% (up to $3,000 annually)
- Weekly in-office lunch benefit every Tuesday
- 100% company-paid short-term and long-term disability coverage
- Annual wellness and professional development stipend to support your health and growth
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What This Job Offers
Job Type
Full-time
Career Level
Senior
