Senior Manager, Business Assessment

Pfizer • New York City, NY

4d • Hybrid

About The Position

The Senior Manager, Business Assessment (BA) owns discrete commercial assessments and forecasts from end to end, building and defending the models and assumptions that inform investment decisions and external deal terms. The role independently evaluates internal pipeline and business development opportunities against Pfizer’s strategy and investment criteria, working closely with partners across Research & Development, Global Commercial Strategy, US and International commercial organizations, and Business Development. The Senior Manager is expected to work hands-on in the underlying models, apply consistent analytical rigor, provide strategic input on investment trade-offs, and present recommendations directly to executive governance bodies.

The role is anchored in Inflammation & Immunology (I&I) and Specialty Care, covering areas such as respiratory, dermatology, gastroenterology, rheumatology, and rare cardiovascular disease. It also assesses opportunities in oncology, internal medicine, vaccines, emerging technology platforms, and novel modalities. The position is part of Pfizer’s Global Commercial Analytics organization under the Chief Marketing Office.

The role uses AI tooling as a standard part of analytical work, including evidence and literature synthesis, competitive landscaping, model quality checks, code-assisted analysis, and drafting executive materials. Cycle-time gains are expected while maintaining rigor and traceability of assumptions. The position also scopes and manages qualitative and quantitative primary research, works flexibly across therapeutic areas in matrixed teams, and may support category, portfolio, and enterprise-level projects.

Requirements

• Bachelor’s degree and at least 6 years of experience; or master’s degree and at least 5 years of experience; or PhD and at least 1 year of experience.
• Advanced Excel proficiency, including the ability to build, audit, and document multi-tab forecast and valuation models.
• Strong PowerPoint skills for preparing executive-level materials.
• Hands-on experience building or owning quantitative commercial forecast and valuation models, including patient-flow or epidemiology-based demand builds, uptake curves, gross-to-net pricing, probability-of-success risk adjustment, and NPV or rNPV valuation.
• Experience using epidemiology literature, analyst reports, secondary or claims data, primary research, and pricing and market access inputs as the basis for a quantitative forecast.
• Experience presenting analysis and recommendations directly to senior executive audiences and engaging commercial and research leaders at appropriate points in the assessment process.
• Permanent work authorization in the United States; the position requires authorization to work in the U.S. by any employer, and U.S. work visa sponsorship is not available.

Nice To Haves

• Prior experience in biopharma forecasting, life sciences consulting, financial services, or another analytical profession.
• Experience in the business development process, particularly opportunity identification, commercial assessment, and deal structure.
• Prior forecasting experience in I&I and/or Specialty Care disease areas.
• Demonstrated use of AI or LLM tooling in analytical workflows, including evidence synthesis, model quality control, or code-assisted analysis, with traceable and auditable assumptions.
• A track record of delivering an unfavorable or contrarian assessment that held up under senior scrutiny.
• Experience influencing without direct authority in a matrixed organization and supporting or leading cross-functional teams under compressed timelines with incomplete information.
• Working knowledge of healthcare and pharmaceutical industry trends, competitor strategies, US and other major global market dynamics, and the drug development process.
• Breadth of leadership experience and capabilities, including influencing and collaborating with peers, developing and coaching others, and guiding colleagues’ work to achieve meaningful outcomes and business impact.

Responsibilities

• Build and own assessments of pipeline and business development opportunities, including epidemiology-based patient flow, treatment exposure, uptake and diffusion curves, gross-to-net pricing, and risk-adjusted NPV.
• Collaborate with cross-functional partners to ensure analyses are rigorous, transparent, and based on common, well-supported modeling techniques and assumptions.
• Take and defend an independent position, including recommending against an opportunity when analysis does not support it and making assessments on incomplete information when required by decision timelines.
• Gather input from internal experts on clinical development plans, clinical profiles, and commercial evaluations.
• Integrate in-line and business development or pipeline forecasts, connecting assessments to in-line assumptions, cannibalization logic, and Long-Range Forecast revenue projections.
• Use AI tools for evidence and literature synthesis, competitive landscaping, model quality control, code-assisted analysis, and drafting executive materials, while keeping assumptions traceable to their sources.
• Scope and commission qualitative and quantitative primary market research with physicians, key opinion leaders, and patients; manage consulting and vendor resources while following internal customer engagement protocols.
• Develop analytically supported recommendations for investment trade-offs across therapeutic areas and between business development opportunities and internal pipeline investments.
• Determine the appropriate level of analytical rigor and external research needed for the timeline and decision.
• Work flexibly across multiple therapeutic areas in a matrixed team.
• Support category and portfolio-level projects, such as category strategy, knowledge management, best-practice synchronization, and professional development, as well as enterprise initiatives and evaluations.

Benefits

• 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution.
• Paid vacation, holiday, and personal days.
• Paid caregiver, parental, and medical leave.
• Medical, prescription drug, dental, and vision coverage.
• Eligible for participation in Pfizer’s Global Performance Plan, with a bonus target of 17.5% of base salary.
• Eligible to participate in Pfizer’s share-based long-term incentive program.
• Relocation assistance may be available based on business needs and/or eligibility.

What This Job Offers

• Job Type: Full-time
• Career Level: Senior