Senior Manager, Business Assessment

Pfizer•New York, NY
•$124,400 - $207,400•Hybrid

About The Position

Business Assessment (BA) is a highly collaborative team responsible for generating investment cases for pipeline and business development decisions. Within Pfizer’s Global Commercial Analytics organization under the Chief Marketing Office, BA provides independent analysis across the asset lifecycle, applying consistent rigor whether an assessment supports or challenges an investment. The team contributes through thought leadership, epidemiology forecasting, analytical capabilities, and clear communication of complex information. The Senior Manager owns commercial assessments and forecasts end to end, including building models, framing assumptions, and defending the analysis. The role partners with Research & Development, Global Commercial Strategy, US and International commercial organizations, and Business Development to objectively evaluate internal pipeline and external opportunities against strategy and investment criteria. The role is hands-on in the underlying models, works with a high degree of independence, and presents analysis and recommendations directly to executive governance bodies. The Senior Manager provides strategic input into investment trade-offs and promotes consistent assessment and forecasting approaches across internal and external opportunities. The role is anchored in Inflammation & Immunology and Specialty Care, with exposure to respiratory, dermatology, gastroenterology, rheumatology, and rare cardiovascular disease areas, as well as opportunities across oncology, internal medicine, vaccines, emerging technology platforms, and novel modalities.

Requirements

  • Bachelor’s degree and at least 6 years of experience, or a master’s degree and at least 5 years of experience, or a PhD and at least 1 year of experience.
  • Advanced Excel proficiency, including the ability to build, audit, and document multi-tab forecast and valuation models.
  • Strong PowerPoint skills for preparing executive-level materials.
  • Hands-on experience building or owning quantitative commercial forecast and valuation models, including patient-flow or epidemiology-based demand builds, uptake curves, gross-to-net pricing, probability-of-success risk adjustment, and NPV or rNPV valuation.
  • Experience using epidemiology literature, analyst reports, secondary or claims data, primary research, and pricing and market access inputs as the basis for a quantitative forecast.
  • Experience presenting analysis and recommendations directly to senior executive audiences and engaging commercial and research leaders at appropriate points in the assessment process.
  • Ability to influence and collaborate with peers, develop and coach others, and guide colleagues’ work to achieve meaningful outcomes and business impact.
  • Must be authorized to work in the United States by any employer; permanent US work authorization is required. US work visa sponsorship is not available.

Nice To Haves

  • Prior experience in biopharma forecasting, life sciences consulting, financial services, or another analytical profession.
  • Experience in the business development process, particularly opportunity identification, commercial assessment, and deal structure.
  • Prior forecasting experience in Inflammation & Immunology and/or Specialty Care disease areas.
  • Demonstrated use of AI or LLM tools in analytical workflows, including evidence synthesis, model quality control, or code-assisted analysis, with assumptions kept traceable and auditable.
  • A track record of delivering an unfavorable or contrarian assessment that held up under senior scrutiny.
  • Experience influencing without direct authority in a matrixed organization and supporting or leading cross-functional teams under compressed timelines with incomplete information.
  • Working knowledge of healthcare and pharmaceutical industry trends, competitor strategies, dynamics in the US and other major global markets, and the drug development process.

Responsibilities

  • Build and own commercial assessments of pipeline and business development opportunities, including epidemiology-based patient flow, treatment exposure, uptake and diffusion curves, gross-to-net price builds, and risk-adjusted NPV.
  • Develop, document, and defend assumptions and independent recommendations, including recommendations against opportunities when the analysis does not support investment.
  • Gather input from internal experts on clinical development plans, clinical profiles, and commercial evaluations across commercial strategy, insights, medical affairs, market access and pricing, marketing, regional leadership, R&D, and Finance.
  • Integrate in-line and pipeline or business development forecasts, connecting assessments to in-line assumptions, cannibalization logic, and Long-Range Forecast revenue projections.
  • Use AI tools in assessment workflows for evidence and literature synthesis, competitive landscaping, model quality control, code-assisted analysis, and drafting executive materials, while maintaining traceability of assumptions.
  • Scope and commission qualitative and quantitative primary market research with physicians, key opinion leaders, and patients; manage consulting and vendor resources in accordance with internal customer engagement protocols.
  • Develop analytically supported recommendations for investment trade-offs across therapeutic areas and between business development opportunities and internal pipeline investments.
  • Determine the appropriate level of analytical rigor and external research for the timeline and decision at hand.
  • Work flexibly across multiple therapeutic areas in a matrixed team.
  • Support category, portfolio, and enterprise projects and initiatives using internal forecasts, analyst reports, and other secondary data.
  • Present analysis and recommendations directly to executive governance bodies and senior audiences.
  • Contribute to professional development, knowledge management, best-practice synchronization, and cross-functional team outcomes.

Benefits

  • 401(k) plan with Pfizer matching contributions and an additional Pfizer Retirement Savings Contribution
  • Paid vacation, holiday, and personal days
  • Paid caregiver, parental, and medical leave
  • Medical, prescription drug, dental, and vision coverage
  • Eligibility for the Global Performance Plan, with a bonus target of 17.5% of base salary
  • Eligibility to participate in a share-based long-term incentive program
  • Relocation assistance may be available based on business needs and/or eligibility
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