Senior IT Manager

Cytovale•South San Francisco, CA

1d•Hybrid

About The Position

Cytovale is seeking a hands-on Senior IT Manager to lead day-to-day IT operations while helping build and scale the company’s internal IT capabilities for future growth. This role combines technical execution, operational leadership, strategic planning, and security-minded infrastructure management. At this stage of growth, the Senior IT Manager will personally perform core systems administration and operational IT work, while also serving as a key partner to the Executive Director of Software & Data Systems in shaping IT strategy, roadmaps, governance, and scalable operating models. The ideal candidate is equally comfortable resolving immediate operational needs, improving systems and processes, and planning for where the business is going next. This role is ideal for someone who enjoys being in the tools, taking ownership end-to-end, and helping build a modern IT function in a growing healthcare technology company.

Requirements

10+ years of experience in IT operations, systems administration, or IT infrastructure management
Demonstrated success in a hands-on IT leadership role within a growing organization
Strong experience administering Microsoft 365 and Azure environments
Experience supporting or managing AWS and cloud-based systems
Strong knowledge of modern IT security best practices and operational controls
Experience supporting security/compliance frameworks such as SOC 2, HIPAA, ISO 27001, or similar
Experience writing IT policies, standards, and operational procedures
Experience working with MSPs, consultants, and external vendors
Ability to balance strategic thinking with direct execution

Nice To Haves

Experience in healthcare, diagnostics, biotech, or regulated industries
Familiarity with Intune, Entra ID, Defender, Vanta, ticketing systems, and endpoint tooling
Experience scaling IT in a startup or growth-stage company
Prior team leadership or people management experience

Responsibilities

Personally execute day-to-day IT operations and systems administration activities.
Administer enterprise platforms including Microsoft 365, Azure, endpoint management, identity systems, and core business applications.
Support cloud environments and operational tooling across platforms such as AWS and SaaS ecosystems.
Perform employee onboarding/offboarding, access provisioning, device lifecycle management, and routine maintenance.
Execute system upgrades, patching, and infrastructure improvements.
Partner with the Executive Director of Software & Data Systems to develop Cytovale’s IT strategy and multi-year roadmap.
Anticipate business growth needs and proactively evolve systems, tools, processes, and support models.
Recommend scalable technology solutions that improve efficiency, security, and employee experience.
Help define future organizational structure, staffing needs, and outsourced vs in-house operating models.
Maintain strong operational security posture across endpoints, identity systems, collaboration tools, and cloud environments.
Support and help mature control frameworks such as SOC 2, HIPAA, and other relevant compliance standards.
Implement and monitor IT security best practices including MFA, least privilege access, patch management, logging, backup, and lifecycle controls.
Author, maintain, and improve IT policies, standards, and operational procedures.
Participate in audits, evidence gathering, remediation tracking, and control improvements.
Own incident, request, and change management workflows to ensure timely service delivery.
Define and improve SLAs, ticket workflows, escalation paths, and support performance metrics.
Track and manage assets, software licensing, vendor renewals, and inventories.
Build runbooks, documentation, and repeatable support processes.
Partner with the Executive Director of Software & Data Systems in coordinating work with Cytovale’s IT MSP and external consultants.
Help define priorities, review recommendations, and ensure strong execution from external partners.
Hold vendors accountable to Cytovale’s standards for quality, responsiveness, security, and cost-effectiveness.
Translate external recommendations into practical implementation plans.