Senior Director - AI

Mayo Clinic•Rochester, MN

About The Position

The Senior Director, AI leads the engineering and research team that builds and delivers Mayo Clinic DigPath's digital-biology technology platforms. The role is accountable for translating the organization's vision into validated, deployed products and, in collaboration with the Vice President, Digital Biology, the Chief Medical Officer, and the Chief Science Officer, shaping technical direction and owning its execution. This includes the roadmap, delivery, and technical quality of DigPath's core model and platform portfolio, including foundation and task-specific models, AI Virtual Cells, biological digital twins, and digital biomarker discovery. The Senior Director directs a multidisciplinary team of AI/ML engineers, software developers, and research scientists. The role translates clinical and scientific priorities into engineering execution, partnering with the CMO on clinical relevance and the CSO on scientific rigor to deliver tools with speed and technical excellence while prioritizing patient needs. The primary responsibility is managing highly matrixed cross-functional activities and personnel, with oversight of departmental AI governance, technology, and operations. The role works alongside Chairs representing the department across Mayo Clinic, partners closely with Shield leaders, and coordinates with other enterprise and Site leaders and governance bodies. This vacancy is not eligible for sponsorship; Mayo Clinic will not sponsor or transfer visas for this position. Mayo Clinic does not participate in the F-1 STEM OPT extension program.

Requirements

  • Bachelor's degree in a relevant field, such as Business Administration, Computer Science, AI/ML Engineering, Software Engineering, Information Systems, Design, or Health Informatics.
  • At least 10 years of related experience.
  • Executive-level management experience with digital, technology, security, or product teams in complex organizations.

Nice To Haves

  • Master's degree in Business, Law, Computer Science, Engineering, Design, Healthcare Administration, or a related field.
  • Experience in integrated healthcare, academic medical centers, or regulated industries.

Responsibilities

  • Lead the engineering and research team building and delivering digital-biology technology platforms.
  • Translate the organization's vision into validated, deployed products.
  • Shape technical direction and own its execution, including the roadmap, delivery, and technical quality of DigPath's core models and platforms.
  • Direct a multidisciplinary team of AI/ML engineers, software developers, and research scientists.
  • Translate clinical and scientific priorities into engineering execution, partnering with the CMO for clinical relevance and the CSO for scientific rigor.
  • Manage highly matrixed cross-functional activities and personnel.
  • Oversee departmental AI governance, technology, and operations.
  • Work with Chairs representing the department across Mayo Clinic, partner with Shield leaders, and coordinate with enterprise and Site leaders and governance bodies.
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