Senior Director, US Marketing Lead – Fabry Disease

BioMarin Pharmaceutical Inc.•San Rafael, CA

About The Position

BioMarin is a leading rare disease biotechnology company focused on genetically defined conditions. Guided by our purpose to develop medicines that make a profound impact on people’s lives, our global teams have delivered a portfolio of therapies since our founding in 1997. Our revolutionary treatments for conditions like achondroplasia (the most common form of dwarfism), PKU (phenylketonuria), CLN2, a form of Batten disease, and a number of forms of MPS (mucopolysaccharidosis) offer new possibilities for patients and families who previously had few, if any, available options. More recently, with the close of the Amicus acquisition, our portfolio has expanded to include therapies for Fabry disease and Pompe disease, expanding our ability to reach more people living with rare genetic conditions. Our success comes from our unwavering commitment to excellence, our deep understanding of patient needs, our scientific expertise, and our world-class manufacturing capabilities. At the heart of BioMarin is a dedicated team of the brightest minds in the industry working together to deliver innovative therapies to patients and families around the world. About Commercial Be part of the worldwide infrastructure that gets our drugs to underserved patients around the world. Our global sales force solidifies BioMarin’s commercial presence in the United States and Europe and is rapidly growing in other regions, such as South America, EuMEA, and Asia-Pacific. Position Overview The Senior Director, US Marketing Lead – Fabry Disease is responsible for defining and leading the end-to-end US commercial strategy for Galafold, BioMarin’s oral therapy for Fabry disease. This role has full accountability for brand performance, including strategic planning, executional excellence, and lifecycle optimization in a complex and evolving rare disease landscape. As a senior commercial leader, this individual will set the strategic vision for the brand, drive cross-functional alignment, and ensure flawless execution across all customer segments. The role requires a highly experienced leader who can influence across the organization without direct authority, navigate ambiguity, and deliver results in a dynamic and competitive environment. The Senior Director will serve as the primary US commercial representative for Galafold, partnering closely with the global Enzyme Therapies (ET) BU marketing team, Market Access, Medical Affairs, Sales, Patient Services, and other key stakeholders to maximize patient impact and business performance. This role reports to the US Head of Marketing, Enzyme Therapies, and serves as a key member of the US Marketing Leadership Team. The Senior Director will lead and develop a high-performing brand team, including direct management of an Associate Director, while fostering a culture of accountability, innovation, and continuous learning.

Requirements

Minimum 12–15+ years of progressive experience in the biotechnology/pharmaceutical industry, with significant US marketing leadership experience.
Proven track record of leading brands in rare disease and/or specialty markets; orphan drug experience strongly preferred.
Demonstrated success in strategic planning, brand growth, and lifecycle management.
Experience operating in complex, highly matrixed organizations, with strong ability to influence without authority.
Deep understanding of the US healthcare ecosystem, including reimbursement, patient services, and access dynamics.
Strong analytical, strategic thinking, and problem-solving capabilities.
Exceptional leadership, communication, and stakeholder management skills.
Experience leading and developing high-performing teams.
Bachelor’s degree required

Nice To Haves

MBA or advanced degree preferred

Responsibilities

Own and define the US brand strategy for Galafold, including long-term vision, annual planning, and lifecycle management.
Drive commercial excellence through innovative strategies, including patient identification, diagnosis acceleration, and treatment optimization.
Establish clear performance objectives, KPIs, and success metrics aligned with business goals.
Serve as the strategic thought partner to Global BU teams, ensuring US insights shape global strategy and execution.
Lead the development and execution of integrated omnichannel marketing programs for HCPs, patients, and caregivers.
Ensure high-quality, compliant, and impactful branded and disease-state education initiatives.
Oversee agency partners and internal teams to deliver best-in-class campaigns and materials.
Drive excellence in POA planning, field engagement, and training, in close partnership with Sales and Commercial Learning & Development.
Influence and align cross-functional stakeholders, including Sales, Market Access, Patient Services, Medical Affairs, Compliance, and Digital.
Lead cross-functional brand team governance, ensuring coordinated execution of strategic priorities.
Partner with Market Access to optimize reimbursement strategy and access dynamics.
Collaborate with Medical Affairs to ensure strong integration of scientific insights and evidence generation.
Lead and represent the brand within US Marketing leadership forums, ensuring alignment of priorities, resource allocation, and organizational focus.
Champion a data-driven and insights-led approach to strategy development.
Lead market research and advisory boards, incorporating perspectives from HCPs, patients, and advocacy groups.
Continuously monitor competitive dynamics and evolving treatment paradigms to inform strategy adjustments.
Directly lead and develop an Associate Director, providing clear strategic direction, coaching, and performance management.
Build and sustain a high-performing brand team, fostering a culture of accountability, agility, and collaboration.
Serve as a talent developer and organizational leader, contributing to capability building across the US Marketing organization.
Model BioMarin leadership behaviors and drive engagement, inclusion, and high standards of execution across the team.