Senior Director of Accounting and Finance

RhyGaze AG • Philadelphia, PA

65d • Hybrid

About The Position

RhyGaze is a biotech company developing gene therapies for patients with blinding retinal diseases. The Senior Director of Accounting and Finance will support the growth and maturation of the Company’s finance organization, providing leadership across accounting, financial planning and analysis, reporting, controls, budgeting, forecasting, and operational finance. The role combines strong technical accounting expertise with hands-on FP&A work in a fast-paced, growing biotech environment.

The position is based in Philadelphia, with an expectation of working onsite three days per week. Candidates must be legally able to work in the United States, as a U.S. citizen or with a U.S. work permit.

Requirements

• Bachelor’s degree in Accounting, Finance, or a related field.
• CPA strongly preferred.
• 8–10+ years of progressive finance and accounting experience, preferably in biotech, life sciences, or a high-growth company environment.
• Experience across both accounting and FP&A.
• Strong understanding of U.S. GAAP.
• Experience with budgeting, forecasting, variance analysis, cash planning, and board-level reporting.
• Ability to work both strategically and hands-on in a lean finance environment.
• Strong analytical, communication, and project management skills.
• Experience working with external auditors, tax advisors, legal counsel, and cross-functional business partners.
• Ability to manage ambiguity, build processes, and improve finance infrastructure as the Company scales.
• Must be legally able to work in the United States as a U.S. citizen or with a U.S. work permit.

Nice To Haves

• Public company readiness, audit, or SOX/control experience.
• Experience with Swiss GAAP and/or IFRS.
• Biotech or pharmaceutical industry experience.
• Pre-IPO, IPO readiness, or public company experience.
• Global finance and accounting leadership experience, including multinational accounting operations, financial reporting, compliance, and business partnering.
• Experience with ERP implementation or finance systems transformation.
• Experience supporting investor, Audit Committee, or Board reporting.
• Familiarity with equity management, 409A valuations, transfer pricing, and international entity structures.

Responsibilities

• Lead core accounting activities, including month-end close, accruals, prepaids, account reconciliations, and financial statement preparation.
• Support preparation of consolidated financial statements and management reporting packages.
• Partner with external auditors and support annual audits, including schedules, documentation, and follow-up items.
• Develop and enhance finance processes, controls, policies, and procedures as the Company scales.
• Lead or support annual budgeting, quarterly forecasting, long-range planning, and scenario modeling.
• Partner with functional leaders to manage department budgets, track spending, analyze variances, and identify risks and opportunities.
• Support financial reporting and analysis for management, the Audit Committee, Board of Directors, and investors.
• Support cash forecasting, runway analysis, financing scenarios, and capital planning.
• Assist with ERP, procurement, expense management, and other finance system and process improvement initiatives.
• Support tax, transfer pricing, intercompany, equity management, and compliance workstreams with internal and external advisors.
• Help build a finance organization capable of supporting future growth, financing activities, and potential public company readiness.
• Support global payroll operations and help ensure accurate, timely, and compliant payroll processing across jurisdictions.
• Support global risk management and insurance programs, including policy administration, renewals, claims management, and broker relationships.

Benefits

• Opportunity to help develop breakthrough therapies for patients with serious vision-threatening diseases.
• Work alongside a passionate, highly experienced team at the forefront of ophthalmology innovation.
• Meaningful impact in a growing biotech company.
• Collaborative, entrepreneurial culture where science and innovation drive decision-making.

What This Job Offers

• Job Type: Full-time
• Career Level: Senior