Senior Director, Global Scientific Content

Madrigal Pharmaceuticals•Conshohocken, PA

33d•$275,000 - $336,000•Hybrid

About The Position

Madrigal is a biopharmaceutical company focused on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH), a serious liver disease that can progress to cirrhosis, liver failure, need for liver transplantation and premature mortality. Every member of our Madrigal team is connected by our shared purpose: leading the fight against MASH. Madrigal’s medication, Rezdiffra (resmetirom), is a once-daily, oral, liver-directed THR-β agonist designed to target key underlying causes of MASH. Rezdiffra is the first and only medication approved by both the FDA and European Commission for the treatment of MASH with moderate to advanced fibrosis (F2 to F3). An ongoing Phase 3 outcomes trial is evaluating Rezdiffra for the treatment of compensated MASH cirrhosis (F4c). Our success is driven by our people. We are building a dynamic, inclusive, and high-performing culture that values scientific excellence, operational rigor, and collaboration. To support our continued growth, we are strengthening our workforce strategy to ensure we have the right talent, at the right time, in the right way. The Senior Director of Global Scientific Content is responsible for leading the development and execution of scientific content within Madrigal Medical Affairs. This role contributes to the Medical Affairs and Scientific Communication Plans, ensuring the globalization and alignment of content initiatives. The Senior Director partners closely with Medical Affairs colleagues to deliver high-quality, impactful scientific content that support both internal stakeholders (e.g., Field Medical, Health Systems) and external stakeholders (e.g., healthcare professionals). These efforts enable effective scientific exchange and communication with impact. The position reports to the Vice President of Scientific Communications (or assigned delegate) and is a hybrid role (three days per week at Conshohocken, PA). All incumbents are responsible for following applicable Division & Madrigal policies and procedures.

Requirements

Advanced degree in a scientific or healthcare discipline (BSc, MD, PharmD, PhD, DNP, etc.)
Rich scientific background with a minimum of 15 years of experience in healthcare / clinical practice
A minimum of 5 years headquarters work and/or Scientific Content experience
Proven ability to understand, communicate, and translate complex scientific information
Knowledge of Scientific Content and Communication trends and landscape
Demonstrated ability to plan, lead and create scientific content
Emphasis on providing leadership though factual evidence gathering influencing and inspiring cross-functional teams to drive innovation and achieve goals
Ability to interact and strategize with leadership and stakeholders across the business
Strong knowledge of US/EU healthcare systems, global regulatory standards (e.g., FDA, CE), and medical affairs compliance standards
Proficiency in Microsoft Office Suite, virtual communication platforms (e.g., Zoom), and CRM systems (e.g., Veeva)
Willingness to travel up to 20% for conferences, various corporate locations, and stakeholder meetings, including overnight trips

Nice To Haves

In-depth knowledge of liver disease; experience in cardiometabolic health, or metabolic dysfunction–associated steatohepatitis (MASH)
Adaptable and proactive in a fast-paced, evolving environment

Responsibilities

Strategic Planning and Alignment Define and prioritize global scientific content needs of internal and external stakeholders, including Health Systems content as appropriate
Ensure scientific content planning is aligned with Madrigal Medical Affairs strategies and Scientific Communication platforms, as well as the training plans
Create and execute the global scientific content plan for the fiscal year, including alignment with the Medical Plan, detailed tactics, interdependencies, ownership, and budget
Content Development Oversee the creation, adaptation, and distribution of global content across multiple channels to deliver consistent and impactful information for scientific exchange
Support the development of comprehensive content strategies that leverage digital and omnichannel approaches to enhance engagement with healthcare professionals (HCPs) and internal stakeholders, ensuring alignment with scientific communication platform within compliance and practice standards
Ascertain scientific accuracy, stakeholder relevance, and appropriateness of the various formats utilized across all the scientific content materials
Champion unwavering commitment to scientific rigor and data-driven decision-making
Alignment with Training Ensure alignment with global scientific training program for field medical and other relevant stakeholders, ensuring best in class training on new content
Gather key insights and key learnings from the evaluation of the impact of training initiatives by analyzing metrics and feedback, ensuring insights are considered for scientific content
Team Leadership & Development Lead, inspire, and develop a high-performing global scientific content team, fostering an inclusive culture of scientific excellence, accountability, and collaboration
Provide mentoring, coaching, and growth opportunities to ensure ongoing development of team members and future leaders
Align all global content strategy and execution activities with organizational strategic objectives and tactical imperatives, serving as a key thought leader and advisor within Medical Affairs
Cross-functional Collaboration Partner with internal cross-functional and regional teams to align on scientific content priorities
Accountability for the collaboration with external vendors and partners as needed to support content deliverables
Contribute to launch readiness and support lifecycle medical affairs activities in alignment with strategic objectives
Congress & External Engagement Contribute to U.S. and global medical congress activities, as needed, including support for booth content, scientific content and training
Compliance & Quality Ensure all activities comply with company SOPs, industry standards, and applicable regulations
Uphold the highest ethical standards in all external engagements

Benefits

equity
flexible paid time off
medical
dental
vision
life/disability insurance
401(k) offerings (i.e., traditional, Roth, and employer match) in accordance with applicable plans
supplemental life insurance
legal services
mental health benefits through our Employee Assistance Program for employees and their family