RWE lead - BRUKINSA)

BeiGene

1d•$222,000 - $292,000

About The Position

The Global HEOR/RWE Senior Director will provide strategic leadership for HEOR and RWE activities supporting BRUKINSA across hematology indications and lifecycle management. This role is accountable for developing and executing integrated value evidence generation strategy to strengthen value proposition and differentiation, support medical, regulatory, commercial and reimbursement needs across key markets. Core responsibilities include comparative effectiveness and real-world evidence generation, JCA/HTA and reimbursement submissions, GVD and AMCP dossiers, indirect comparisons, health economic modeling, and HEOR/RWE data dissemination. The Senior Director will serve as a key strategic cross-functional partner to medical, commercial, clinical development, and regulatory to ensure aligned evidence generation. This position requires strong research expertise, strategic and innovative thinking with an understanding of reimbursement systems and the evolving treatment landscape, strong communication and presentation skills, and the ability to lead and drive results in a matrix environment.

Requirements

Advanced degree in Health Economics Outcomes Research (HEOR), Epidemiology, Public Health, Biostatistics, or related discipline
PhD with 6+ years or Master’s degree with 8+ years of related experience in biopharmaceutical industry or consulting
Hematology/Oncology experience strongly preferred
Demonstrated experience serving as HEOR/RWE lead supporting product launch and lifecycle management
Proven success leading and executing evidence generation strategy and HEOR deliverables
Strong understanding of global market dynamics and reimbursement landscape, with experiences supporting HTA and/or JCA submissions
Demonstrated research expertise in designing and conducting HEOR/RWE studies, including indirect comparison, economic models and comparative effectiveness studies, with success in data dissemination and communication
Impactful communication and presentation skills, with the ability to translate complex data and engage diverse stakeholders
Innovative thinking and creative mindset with applied AI understanding to enhance evidence generation and HEOR insights
Highly organized and self-motivated with ability to effectively prioritize and manage multiple projects, determine and meet objectives, timelines, and budget
Ability to work in a cross-functional matrix team environment and effectively communicate and collaborate relevant HEOR/RWE strategies and activities with internal and external stakeholders
Proficiency in Microsoft Office, familiarity with statistical software, HEOR modeling tools and AI-enabled approaches for evidence generation and communication

Nice To Haves

Hematology/Oncology experience strongly preferred

Responsibilities

Lead and drive global HEOR/RWE strategy and evidence generation activities for BRUKINSA across indications and throughout the product lifecycle, ensuring alignment with cross-functional objectives
Identify evidence gaps and opportunities, develop and execute integrated value evidence generation plan (including disease burden, treatment patterns, comparative effectiveness, indirect comparisons, economic modeling, and patient-centered outcomes) to strengthen differentiation and demonstrate clinical and economic value
Design and execute real-world evidence and comparative effectiveness studies using various real-world data sources including claims and electronic health records to support differentiation
Demonstrate agility in responding to emerging competitor data and evolving evidence needs, including proactively monitor and assess the evolving clinical, competitive, payer, and evidence landscape for BRUKINSA and relevant hematologic malignancies, timely assessment of evidence gaps and development of HEOR/RWE analyses and evidence-generation strategies to support differentiation and value demonstration
Collaborate with cross-functional partners on payer/JCA/HTA submissions and lead key HEOR deliverables timely including indirect comparisons and economic modeling
Lead development of Global Value Dossiers and US AMCP dossier to support reimbursement submissions and value communication
Lead development of health economic models, including cost-effectiveness and budget impact analyses
Drive HEOR/RWE publication strategy and scientific dissemination of HEOR/RWE evidence through abstracts, manuscripts, congress presentations and omnichannel distributions
Partner cross-functionally with Clinical Development, Biostatistics, Medical Affairs, Regulatory, Commercial, and Market Access teams to integrate HEOR insights into overall program strategy
Manage external vendors and research partners, overseeing study design, project executions, deliverables, timelines, and budgets
Provide strategic HEOR guidance to affiliates and regional teams to support local evidence needs