Real World Evidence Manager

Vertex Inc.•Boston, MA

1d•$132,100 - $198,100•Hybrid

About The Position

The Real World Evidence Manager is an integral member of the RWE team who leverages expertise in epidemiology, real world data, and other relevant disciplines to assess the natural history and real world outcomes for Vertex’s pipeline and portfolio products. The position will support cross-functional global observational research by providing methodological and analytical support for internal stakeholders, including Clinical Development, Global Medical Affairs, Global Patient Safety, and Government Affairs and Public Policy. The Manager will also execute on tactics related to the collection and/or analysis of real world data to inform relevant stakeholders such as regulatory affairs and clinical development.

Requirements

Working knowledge of relevant RWE regulatory agency guidance and position papers and the opportunities to use RWE to inform regulatory decision making
Demonstrated ability to design and execute observational research
Strong interpersonal communication and study management skills
Ability to take detailed observational study results and communicate them in a clear, non- technical manner to internal cross-functional teams, using language that resonates with the teams, while maintaining the integrity of key findings
Ability to work collaboratively in a constantly changing, diverse, and matrix environment
Minimum 2 years of experience working in observational research within the life sciences industry or relevant academic, government, or consulting environment

Responsibilities

Support focused/targeted epidemiologic research in support of Vertex’s pipeline and established portfolios, including Natural History (NH) of disease and systematic literature reviews
Ensure scientific rigor for real world data analyses
Conduct feasibility assessment of relevant data sources for disease areas and research questions
Provide insights and experience to design and defend fit-for-purpose epidemiologic observational research; Identify appropriate analytic methods aligned to research needs
Collaborate with and manage vendors, to ensure meeting project timelines and goals
Support Study Execution Teams for observational studies
Contribute to development of performance metrics and dashboards for RWE projects
Able to balance multiple projects in a fast-paced environment
Utilize strong oral and visual communication skills and understanding of Vertex strategies to promote and translate value of RWD/RWE methods and studies across the company
Excellent communication skills (oral and written) with internal and external audiences
Contribute to company publications strategy via development of conference abstracts, presentations, peer- reviewed manuscripts based on the findings of RWE studies