Senior Director, Device Portfolio Insights

Eli Lilly and Company • Indianapolis, IN

1d

About The Position

The Senior Director of Device Portfolio Insights serves as enterprise owner of device portfolio strategy, investment prioritization, and long-range value creation. This role orchestrates cross-functional integration across R&D, Clinical, Therapeutic Areas, Commercial, Finance, and Digital to drive portfolio decisions that maximize strategic and financial return. This leader provides oversight of portfolio health, prioritization, and governance while ensuring integration between drug delivery devices and Lilly's clinical pipeline. Serving as the central hub for portfolio intelligence, this role drives resource allocation, investment optimization, and AI-enabled decision support. The position requires sophisticated analytical capabilities and the ability to synthesize complex information into actionable insights that guide executive decision-making.

Requirements

• Bachelor's degree in relevant discipline (Business, Engineering, Life Sciences, Data Science, Operations Research) with a minimum of 15 years of experience in pharmaceutical and medical device R&D, portfolio management, strategy, or related functions
• Proven track record managing complex, multi-million-dollar portfolios with cross-functional dependencies
• Significant experience with drug delivery systems, medical devices, or combination products
• Demonstrated experience in resource management and capacity planning for R&D organizations
• Experience with pharmaceutical governance processes and investment decision-making
• Strong background in financial analysis, business case development, and investment optimization

Nice To Haves

• Master's degree (MBA, MS) in relevant discipline (Business, Engineering, Life Sciences, Data Science, Operations Research) with 10+ years of progressive experience in pharmaceutical and medical device R&D, portfolio management, strategy, or related functions, OR PhD with 5+ years of experience as listed above
• Deep knowledge of portfolio management principles, frameworks, and best practices
• Experience with portfolio optimization methodologies and decision analysis techniques
• Proficiency with portfolio management tools and software (e.g., Planisware, Clarity, ServiceNow, Tableau)
• Understanding of stage-gate processes and governance frameworks in pharmaceutical R&D
• Knowledge of portfolio metrics, KPIs, and performance measurement systems
• Experience with agile portfolio management and adaptive planning approaches

Responsibilities

• Develop and maintain a comprehensive, integrated view of the device development portfolio spanning drug delivery pre-clinical & clinical research, device innovation, development, and commercialization projects, programs, and initiatives under device development
• Ensure seamless integration between drug delivery device development and Lilly's clinical molecule pipeline across all therapeutic areas
• Support annual portfolio strategic planning processes in collaboration with device development leadership
• Use market analysis, competitive intelligence, and technology assessments to inform portfolio strategy
• Identify whitespace opportunities and recommend new investment areas.
• Support build vs. buy vs. partner analyses for delivery system capabilities
• Leverage deep portfolio knowledge and financial expertise to optimize investment strategies at both project and portfolio levels
• Partner with Finance and PPM/CMC PM teams to develop accurate cost models, forecasts, and business cases for drug delivery system initiatives
• Track and report on portfolio expenditures, variance analysis, productivity, and return on investment metrics
• Support business case development for new initiatives and portfolio prioritization decisions
• Develop and update device development archetypes and support disease state benchmarking activities
• Develop, maintain, and continuously enhance the device development portfolio dashboard to support data-driven decision-making
• Establish key performance indicators (KPIs) and metrics that provide meaningful insights into portfolio health, progress, and value realization
• Create visualizations and reporting tools that enable leadership to quickly assess portfolio status, risks, and opportunities
• Implement predictive analytics and modeling capabilities to forecast portfolio outcomes
• Champion use of decision science, data science, and AI applications in device development business intelligence to improve portfolio operations
• Deploy predictive analytics and decision augmentation tools to enhance portfolio forecasting, risk assessment, scenario planning, and opportunity identification
• Identify resource constraints, bottlenecks, and capability gaps; recommend solutions
• Monitor resource utilization metrics and drive continuous improvement in capacity management
• Ensure clear and consistent communication of portfolio status, insights, and recommendations to device development leadership and cross-functional stakeholders
• Facilitate regular portfolio communication forums to share insights, trends, and priority shifts
• Identify, assess, and communicate portfolio-level risks, dependencies, and integration challenges.
• Develop risk mitigation strategies and contingency plans for high-impact portfolio risks
• Ensure transparent escalation of critical issues requiring leadership attention or intervention
• Build strong relationships with therapeutic area leaders, clinical development teams, and commercial stakeholders
• Translate complex portfolio data into compelling narratives for executive audiences
• Prepare portfolio materials for governance reviews, decision forums, and executive leadership meetings
• Ensure governance readiness by maintaining current, accurate data on milestones, deliverables, risks, and dependencies
• Act as a trusted advisor to leadership on portfolio strategy and investment decisions

Benefits

• company bonus (depending, in part, on company and individual performance)
• company-sponsored 401(k)
• pension
• vacation benefits
• medical, dental, vision and prescription drug benefits
• flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts)
• life insurance and death benefits
• certain time off and leave of absence benefits
• well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities)

What This Job Offers

• Job Type: Full-time
• Career Level: Senior
• Number of Employees: 5,001-10,000 employees