Senior Director, Commercial Finance

Achieve Life Sciences

12d•$260,000 - $280,000•Remote

About The Position

The Senior Director, Commercial Finance will serve as the senior finance partner to Achieve Life Sciences’ commercial leadership team as the company prepares for the potential commercial launch of cytisinicline. Reporting to the Chief Financial Officer, this leader will provide strategic advice and hands-on financial analysis to guide commercial strategy, investment decisions, resource allocation, and financial discipline as the organization transitions toward commercialization. The role owns commercial planning and forecasting, including annual and long-range plans, rolling forecasts, revenue and gross-to-net modeling, and commercial operating expenses. It partners with Sales, Marketing, Market Access, Commercial Operations, IT, and Accounting to assess commercial performance, improve data and reporting capabilities, evaluate program returns, and support sound investment decisions. The position is remote, with candidates able to reside anywhere in the continental United States, and may require up to 10% travel for conferences and company meetings.

Requirements

Bachelor’s degree in Finance, Accounting, Economics, or a related field.
12+ years of progressive FP&A or commercial finance experience, including 5+ years in a leadership role.
Direct experience supporting sales and commercial organizations; biopharma or life sciences experience is ideal.
Proven track record developing ROI frameworks and business cases to evaluate commercial or marketing investments.
Advanced financial modeling skills, including revenue forecasting, driver-based planning, and scenario analysis.
Strong working knowledge of gross-to-net, payer dynamics, and commercial operating models.
Excellent communication and presentation skills, including experience presenting financial analyses and recommendations to executive leadership teams and Boards.
Strategic thinking and sound business judgment, with the ability to translate complex financial analyses into clear, actionable recommendations.
Ability to balance hands-on analytical work with strategic partnership in a growing, evolving organization.

Nice To Haves

MBA, CPA, or CFA.
Experience supporting a U.S. product launch or a commercial organization during its early stages of growth.
Familiarity with promotional response analysis, marketing-mix modeling, or test-and-control measurement methodologies.
Hands-on experience with financial planning and business intelligence tools such as Adaptive, Anaplan, Power BI, or Tableau.
Experience working with prescription, claims, and specialty pharmacy data.

Responsibilities

Own annual operating plans, long-range plans, and rolling forecasts across commercial functions, including revenue, gross-to-net, and commercial operating expenses.
Build and maintain driver-based revenue forecasts covering demand, prescriptions, pricing, payer mix, channel dynamics, and inventory.
Translate commercial priorities into financial targets, resource plans, and budgets.
Conduct scenario and sensitivity analyses to support launch planning, pricing decisions, and commercial investment priorities.
Serve as a finance partner to commercial leaders, connecting strategy, operating performance, and financial outcomes.
Partner with Sales leadership on field force sizing, territory deployment, incentive compensation design, and quota setting.
Work with Marketing and Market Access to evaluate brand budgets, payer contracting economics, and patient support program costs.
Challenge assumptions, identify financial trade-offs, and recommend actions to maximize commercial investment returns.
Lead monthly and quarterly business reviews, including variance analysis, key performance drivers, and recommended actions.
Develop and maintain dashboards for revenue, demand, productivity, and spend efficiency.
Prepare commercial financial analyses and presentations for executive leadership, the Board of Directors, and investor communications.
Work with Accounting on commercial accruals, gross-to-net reserves, and month-end close activities for commercial cost centers.
Strengthen financial planning tools, data infrastructure, and reporting processes as the commercial organization grows.
Partner with Commercial Operations and IT to integrate data across CRM, specialty pharmacy, claims, and syndicated data sources.
Establish and reinforce spend controls, purchase approval processes, and adherence to company policies.
Design and own a standardized ROI framework for promotional, field, digital, patient support, payer, and HCP engagement programs.
Establish program baselines, success metrics, and attribution methods with Marketing, Sales, and Commercial Analytics before launch.
Evaluate program effects on demand, new patient starts, persistence, and revenue using appropriate methods, including test-and-control, pre/post analysis, and marketing-mix approaches where applicable.
Compare actual program spending and outcomes with original assumptions and provide regular performance updates to leadership.
Recommend reallocating resources from lower-return activities to higher-return programs, with recommendations to scale, modify, or discontinue investments.
Develop financial models and business cases for proposed commercial programs, vendors, and channel investments, assessing costs, revenue impact, payback periods, risks, and assumptions.
Establish a stage-gate process for piloting new initiatives with defined success criteria, milestones, and decision points.
Compare proposed investments with existing commercial investments to support portfolio trade-offs and resource allocation.