Senior Director, Clinical Development (MD)
About The Position
The Senior Medical Director provides strategic and scientific leadership for one or more oncology development programs, serving as the clinical development lead from early development through registration planning, as applicable. The role shapes clinical development strategy, oversees execution across multiple studies, and partners with cross-functional teams to advance programs in alignment with corporate objectives. The position influences development decisions, represents clinical development to senior leadership and external stakeholders, and contributes to portfolio and lifecycle planning. The role also includes mentoring junior physicians and, as applicable, contributing to portfolio strategy, business development evaluations, and external innovation assessments. Travel of up to 25% is expected.
Requirements
- MD or DO degree.
- At least 6 years of clinical, scientific, and/or drug development experience, including substantial experience in biopharmaceutical clinical development.
Nice To Haves
- Board certification in Hematology/Oncology or a related specialty.
- Significant experience leading oncology drug development programs with responsibility for clinical strategy and execution.
- Demonstrated experience leading first-in-human, proof-of-concept, and registrational development programs.
- Cell therapy experience, including autologous, allogeneic, and/or in vivo cellular therapy platforms.
- Experience leading interactions with global health authorities and supporting major regulatory submissions.
- Demonstrated ability to influence cross-functional teams and drive decision-making in a matrix environment.
- A track record of scientific leadership through publications, presentations, advisory boards, and engagement with external experts and key opinion leaders.
- Experience mentoring and developing physicians, scientists, and cross-functional team members.
- Strong strategic thinking and ability to balance scientific rigor, operational feasibility, regulatory requirements, and business objectives.
- Experience evaluating external innovation, licensing opportunities, partnerships, or business development transactions.
- Ability to thrive in a dynamic and evolving environment and manage competing priorities with minimal direction.
- Willingness to travel up to 25%.
Responsibilities
- Lead clinical development strategy for one or more oncology programs, providing scientific and medical leadership from IND-enabling activities through proof-of-concept and early development milestones.
- Provide clinical oversight and medical monitoring across one or more clinical studies, ensuring participant safety, data integrity, and high-quality execution.
- Lead cross-functional teams in the design, implementation, and execution of clinical development plans and clinical studies.
- Author and review protocols, investigator brochures, clinical study reports, regulatory documents, and other key clinical development deliverables.
- Provide strategic leadership for regulatory interactions and submissions, including INDs, health authority meetings, and regulatory responses, as applicable.
- Collaborate with Research, Translational Sciences, Clinical Operations, Safety, Regulatory Affairs, and CMC teams to advance development programs and achieve key milestones.
- Build and maintain relationships with investigators, key opinion leaders, scientific advisors, and other external stakeholders.
- Present clinical data and development strategies to governance committees, health authorities, scientific conferences, and investigator meetings.
- Lead or contribute to scientific publications and presentations.
- Mentor junior physicians and contribute to portfolio strategy, business development evaluations, and external innovation assessments, as applicable.
- Create inclusion, develop talent, and empower teams by modeling inclusion, coaching employees, aligning team goals with organizational objectives, and helping remove barriers.
Benefits
- May be eligible for a discretionary annual bonus.
- May be eligible for discretionary stock-based long-term incentives; eligibility may vary by role.
- Paid time off.
- Company-sponsored medical insurance.
- Company-sponsored dental insurance.
- Company-sponsored vision insurance.
- Company-sponsored life insurance.
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What This Job Offers
Job Type
Full-time
Career Level
Senior
Education Level
Ph.D. or professional degree
