Senior Director, Clinical Development (MD) Inflammatory Bowel Disease (IBD)

Gilead Sciences•Foster City, CA

3d•$302,005 - $390,830•Onsite

About The Position

The Senior Director, Clinical Development (MD), Inflammation and Immunology, is a physician-leadership role responsible for shaping and advancing clinical development strategies across inflammatory bowel disease (IBD) programs. As Clinical Development Lead and Physician Responsible, the role defines clinical vision for assigned molecules and products, guiding decisions from early strategy through regulatory engagement and lifecycle execution. The position works with global cross-functional leaders to advance therapies, generate clinical evidence, and address unmet needs among patients with IBD. The role requires regular on-site work in Foster City, California. It is not eligible for remote or hybrid arrangements; candidates must live locally or relocate before their start date. The Senior Director leads clinical development strategy and execution, including protocol design, study conduct, medical monitoring, data interpretation, and reporting. The role represents clinical development in governance and portfolio forums, contributes to regulatory strategy and submissions, leads scientific communications, and builds relationships with investigators, key opinion leaders, and external scientific experts. It also supports resource planning and investment stewardship and may lead and develop direct reports. People-leader expectations include creating inclusion, developing talent through coaching and feedback, and empowering teams by aligning goals, reinforcing accountability, removing barriers, and connecting employees to the broader organization. The salary range is $302,005 to $390,830. The position may also be eligible for a discretionary annual bonus, discretionary stock-based long-term incentives, paid time off, and company-sponsored medical, dental, vision, and life insurance, subject to applicable plan terms and eligibility.

Requirements

MD degree.
At least 10 years of relevant clinical, scientific, and/or drug-development experience in industry, academia, or a combination of both.
Substantial clinical development experience and demonstrated leadership establishing and executing Phase 2 clinical development programs.
Experience contributing to or leading Phase 3 development.
Must live locally or relocate before the start date; regular on-site work in Foster City, California is required.
Strong knowledge of clinical trial design, endpoints, statistics, safety assessment, dose selection, and drug-development principles.
Demonstrated ability to critically evaluate emerging biological and clinical data and translate findings into development decisions.
Experience providing clinical and scientific leadership across investigator and site selection, study initiation, trial execution, and ongoing medical oversight.
Experience engaging with global regulatory authorities and contributing to regulatory strategies, interactions, and submissions supporting late-stage development.
Demonstrated success leading complex, cross-functional drug-development programs in a global, matrixed environment and influencing senior stakeholders without direct authority.
Exceptional written and verbal communication skills, including the ability to translate complex scientific and clinical information into clear recommendations for senior leaders, cross-functional partners, and non-specialist audiences.

Nice To Haves

Clinical training, board certification, or substantial drug-development expertise in dermatology, allergy/immunology, rheumatology, pulmonary medicine, or a related specialty.
Significant clinical development experience across inflammatory and immunologic diseases; experience in atopic dermatitis, hidradenitis suppurativa, psoriasis, IBD, asthma, COPD, or related immune-mediated diseases is preferred.
Experience developing Phase 2 clinical strategy and protocols, initiating and executing interventional trials, interpreting proof-of-concept and dose-finding data, and translating Phase 2 findings into Phase 3 development strategies.
Experience leading global Phase 3 development programs, including clinical strategy, trial design, protocol development, study initiation and execution, medical monitoring, data interpretation, reporting, and benefit-risk assessment.
Experience developing small molecules, biologics, and/or novel targeted modalities for immune-mediated diseases.
Experience developing and applying pharmacodynamic, translational, patient-selection, and/or disease biomarkers to support clinical development decisions.
People-leadership experience, including managing organizational resources and significant program budgets.
Experience presenting clinical development strategies, data, and recommendations to executive leadership and governance committees.
Extensive experience authoring, reviewing, or overseeing clinical publications and scientific presentations.
Established relationships with investigators, key opinion leaders, and external scientific experts in dermatology, immunology, inflammation, or related disease areas.

Responsibilities

Define clinical development strategies and plans for assigned IBD assets.
Provide physician leadership across programs, ensuring scientific rigor and patient-centered decisions.
Represent clinical development in governance, steering, and portfolio-review forums.
Shape development priorities, risk assessments, and investment decisions.
Lead protocol design, study conduct, medical monitoring, data interpretation, and reporting.
Oversee trial execution to ensure quality, compliance, patient safety, and operational excellence, including site engagement.
Provide clinical expertise on eligibility criteria, safety assessments, toxicity management, and benefit-risk evaluation.
Guide development teams in achieving key milestones, deliverables, and reporting of clinical results.
Lead clinical strategy discussions with global health authorities.
Direct clinical development content for regulatory submissions, investigator brochures, and related documents.
Advance scientific communications, publications, congress presentations, and investigator meetings.
Ensure development activities meet regulatory expectations and Good Clinical Practice standards.
Lead and influence global, cross-functional development teams.
Build relationships with key opinion leaders, investigators, and external scientific experts.
Provide clinical input on business development opportunities, as appropriate.
Communicate program strategy and progress to senior leaders and executive stakeholders.
Ensure compliance with Gilead SOPs, regulatory requirements, and industry standards.
Support resource planning and responsible stewardship of development investments.
May lead and develop direct reports and foster a high-performance culture.
Create inclusion by modeling inclusive behavior and embedding diversity in day-to-day people leadership.
Develop talent through coaching, performance and growth support, and feedback.
Empower teams by aligning goals and objectives, reinforcing accountability, removing barriers, and providing access to the broader organization.