Senior Clinical Trial Manager - Oncology (US)

Worldwide Clinical Trials•Durham, NC
•$112,000 - $222,000•Remote

About The Position

As a Senior Clinical Trial Manager, you'll play a pivotal role in leading clinical site management activities that help bring innovative therapies to patients who need them most. Your leadership will directly support the successful execution of clinical trials, ensuring quality, efficiency, and excellence from study start-up through closeout. Working closely with sponsors, CRAs, and cross-functional project teams, you'll serve as a key strategic partner responsible for driving clinical monitoring activities and delivering high-quality outcomes. This is an opportunity to make a meaningful impact while guiding teams through complex clinical research programs in a collaborative, patient-focused environment. At Worldwide, you'll join a values-driven culture where leaders work alongside their teams and where every clinical trial is approached with the care, urgency, and commitment patients deserve.

Requirements

  • Bachelor’s Degree or Nursing Degree, plus 2+ years of experience as a Clinical Trial Manager, Clinical Operations Leader, Clinical Trial Lead, or equivalent role.
  • 4+ years of experience as a Clinical Research Associate.
  • Ability to travel up to 25%; valid passport required.
  • Required experience supporting Oncology clinical trials.
  • Demonstrated ability to lead, motivate, and support remote teams.

Responsibilities

  • Lead and provide direction to Clinical Research Associates and site management team members throughout the full study lifecycle.
  • Serve as the primary Site Management representative for clinical monitoring and site activities across assigned projects.
  • Act as a key sponsor-facing contact, building strong partnerships and ensuring effective communication throughout study execution.
  • Oversee monitoring deliverables to support study objectives, quality expectations, and budget requirements.
  • Identify and manage out-of-scope activities while proactively communicating potential impacts and solutions.
  • Drive collaboration across cross-functional teams to ensure consistent execution of clinical site management activities.
  • Support high-quality study conduct by providing leadership, guidance, and operational oversight to project teams.

Benefits

  • Competitive benefits package
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