Senior Clinical Trial Manager

ICON plc • Montreal, QC

2d • Remote

About The Position

ICON is a global healthcare intelligence and clinical research organisation united by a mission to bring new medicines and treatments to patients faster. As a values-driven organisation, integrity, collaboration, agility, and inclusion are at the heart of how we work and interact with each other, customers, patients and suppliers. We are currently seeking a Senior Clinical Trial Manager to join our diverse and dynamic team at ICON. In this critical leadership role, you will oversee the operational delivery of clinical trials from study start-up through closeout, ensuring quality, compliance, and execution against study timelines and objectives. As the clinical operations lead, you will work cross-functionally with sponsors, investigators, vendors, and internal stakeholders to drive successful study outcomes while identifying and mitigating risks throughout the trial lifecycle.

Requirements

• Bachelor's degree in Life Sciences, Health Sciences, Nursing, Pharmacy, or another relevant scientific discipline, or an equivalent combination of education and experience.
• Significant Clinical Trial Management experience within a CRO (preferred), pharmaceutical, or biotechnology environment.
• Demonstrated ability to successfully lead and deliver clinical studies from start-up through closeout.
• Strong understanding of clinical trial operations, ICH-GCP, and applicable regulatory requirements.
• Experience managing study timelines, budgets, vendors, and cross-functional stakeholders.
• Proven ability to identify risks, solve complex operational challenges, and drive study execution.

Nice To Haves

• Prior monitoring experience preferred.
• Experience managing global and/or complex clinical trials preferred.

Responsibilities

• Lead the operational delivery of assigned clinical trials, ensuring milestones, timelines, budget expectations, and quality standards are achieved.
• Drive study start-up activities, site activation, enrollment strategies, and study execution through database lock.
• Provide oversight of study progress, monitoring activities, clinical metrics, and site performance.
• Develop and implement effective study oversight plans, monitoring strategies, and risk mitigation approaches.
• Identify operational challenges and proactively implement solutions to ensure successful study delivery.
• Build and maintain strong relationships with sponsors, investigators, vendors, and cross-functional stakeholders.
• Review study performance metrics and provide regular status updates and reporting.
• Support, mentor, and collaborate with Clinical Research Associates (CRAs) and other study team members.
• Ensure all clinical trial activities comply with protocol requirements, ICH-GCP guidelines, and applicable regulatory requirements.

Benefits

• Competitive base salary and performance related incentives
• Health and wellbeing programmes including medical, dental, and vision coverage where applicable
• Retirement and pension plans
• Life assurance and disability coverage
• Employee assistance programmes and wellbeing resources
• Learning and development opportunities through structured training and career pathways

What This Job Offers

• Job Type: Full-time
• Career Level: Senior