Senior Clinical Pharmacologist

AbbVie•San Francisco, CA

6d•$109,500 - $208,500

About The Position

Conceive and execute novel scientific research or development in Clinical Pharmacology to achieve project and Clinical Pharmacology and Pharmacometrics (CPPM) goals. Generate new PK/PD proposals and lead those efforts. Investigate, identify, develop, and optimize new methods and techniques in the PK/PD field. Act as a lead PK scientist in an area of expertise, critically evaluate relevant Clinical Pharmacology, PK/PD, and regulatory advances, and integrate this knowledge into research or development programs.

Requirements

PhD with 0 years of experience, or PharmD with 2+ years of experience in a relevant field, or a master's degree or equivalent education and typically 8+ years of experience, or a bachelor's degree or equivalent education and typically 10+ years of experience.
Relevant field includes experience with PK, PBPK, PK-PD, Pharmacometrics or systems pharmacology, or drug metabolism/transporters.
Excellent interpersonal skills.
Ability to interact externally and internally and perform in a team setting.
Scientific acumen and technical skills to perform the role.
Persistent and resilient; finds ways to move good ideas forward.
Uses mistakes, failure, and reflection as vehicles for learning and improvement.
Delivers business results while positioning AbbVie for long-term success.
Connects unrelated concepts and generates original or unique ideas.
Influences colleagues to achieve cross-functional alignment.

Responsibilities

Contribute to clinical development by supporting Phase 1–4 studies, including study design and clinical pharmacology strategy.
Author regulatory documents, including protocols, study reports, population PK reports, exposure-response analysis reports, relevant sections of investigator brochures, common technical documents, white papers, and similar documents.
Conduct data analyses, including non-compartmental analyses, modeling and simulation, and literature data analyses.
Participate in and present at departmental and cross-functional teams, including study teams, Clinical Pharmacology and Biopharmaceutics, clinical strategy teams, the Clinical Pharmacology leadership team, and journal club.
Collaborate with scientific support from other Clinical Pharmacology functional groups to provide a unified clinical pharmacology position to clinical, CMC, and regulatory teams.
Author scientific publications and present at scientific conferences.
Generate new PK/PD proposals and lead those efforts.
Investigate, identify, develop, and optimize new PK/PD methods and techniques.
Critically evaluate relevant Clinical Pharmacology, PK/PD, and regulatory advances and integrate this knowledge into research or development programs.