Senior Business Analyst, Commercial Operations

Xeris Pharmaceuticals•Chicago, IL

5d•Hybrid

About The Position

The Senior Business Analyst, Commercial Operations, leads integrated commercial analytics and predictive insight generation across Xeris’ portfolio. This role connects independent data streams, identifies performance drivers, develops business triggers for next-best-action opportunities, and applies advanced analytics to support marketing mix, access, patient journey, and commercial investment decisions. The individual will serve as a cross-functional analytics partner to Commercial, Marketing, Market Access, Patient Services, Finance, IT, and external vendors, helping improve revenue predictability, promotional effectiveness, and scalable decision-making across the commercial organization.

Requirements

Bachelor’s degree in business, Analytics, Finance, Economics, Statistics, or related field.
5+ years of experience in pharmaceutical, biotech, medtech, or healthcare commercial operations, sales operations, business analytics, finance, or related function.
Deep experience in commercial analytics within a biopharma or specialty drug context, including promotional effectiveness, field force analytics, or brand performance.
Hands-on experience working with patient-level and longitudinal data, including specialty pharmacy, claims, hub, or payer datasets.
Familiarity with syndicated market data platforms such as IQVIA, PantherRx, and similar data sources.
Hands-on experience with SQL, Python, or R for querying and data analysis
Advanced Excel and PowerPoint skills.
Experience with CRM platforms in a biopharma context, with Veeva CRM strongly preferred.
Strong problem-solving skills with ability to work independently in a fast-paced environment.
Proven ability to manage multiple priorities and influence stakeholders across functions.
Strong written and verbal communication skills.

Nice To Haves

Master’s degree preferred.
Experience in specialty pharma/ retail pharma/rare disease.
Working knowledge of targeting/segmentation, call planning and sequencing processes.
Familiarity with syndicated pharma data sources and field performance data.
Experience supporting launches, new product planning, or evolving commercial models.

Responsibilities

Synthesize and interpret commercial data across CRM, specialty pharmacy, claims, payer/access, marketing engagement, patient services, finance, and internal performance systems.
Develop analytical frameworks that translate fragmented data streams into performance drivers, leading indicators, risk signals, and next-best-action triggers.
Apply predictive analytics and propensity models to identify customer, patient, access, and promotional patterns that inform commercial action.
Lead marketing mix and promotional effectiveness analytics by evaluating channel performance, investment response, audience engagement, and ROI indicators.
Partner with Marketing and Finance to assess commercial investment tradeoffs and quantify risks, opportunities, and expected impact.
Define trigger logic and business rules for commercial alerts, including patient flow disruptions, access friction, adherence risk, promotional response, and underperforming segments.
Lead patient journey and access analytics by integrating payer, SP, claims, and internal data to identify leakage points and intervention opportunities.
Strengthen forecast confidence by monitoring leading indicators and attributing demand variance to specific commercial, access, and market factors.
Translate analytical findings into decision-ready recommendations for commercial leadership, business reviews, and cross-functional planning.
Partner with Business Technology and vendors to define business requirements for data and analytics infrastructure improvements.
Mentor junior analysts and contribute to team capability by establishing analytical standards and leading analytical QA processes.