Senior Brand Director, Obexelimab

Zenas BioPharma•Waltham, MA

About The Position

Zenas is seeking a seasoned, dynamic commercial marketing leader with deep US market understanding and experience in immunology, inflammation and/or rare disease to own the obexelimab brand. Reporting to the VP, Head of Marketing, the Senior Brand Director, Obexelimab will serve as the brand lead for obexelimabs first anticipated commercial indication in IgG4-Related Disease (IgG4-RD) — setting the strategic direction for brand positioning, messaging, customer segmentation across all audiences, market development, launch readiness and commercial execution. As the brand owner for obexelimab in IgG4-RD, this leader will set the strategic vision for the brand and serve as the authoritative voice across the US Brand Team — driving alignment across all customer-facing functions including Marketing, Strategic Engagement, Sales, Market Access, Medical Affairs, Analytics, Patient Services, Legal, Regulatory and Compliance. The role demands a senior strategic marketer with the judgment to make and defend brand choices, the credibility to influence across functions, and the executional acumen to translate insight into focused plans, compelling messages and high-quality launch assets.

Requirements

Bachelor's degree required; advanced degree in business, marketing or life sciences preferred.
12+ years of pharmaceutical or biotechnology marketing experience, including meaningful brand ownership across multiple customer audiences, strategic leadership and launch experience at the Director level or above.
Deep understanding of US market dynamics, specialty pharmaceutical commercialization and cross-functional launch planning.
Demonstrated success developing customer-centric marketing strategy, positioning, messaging and promotional/disease education assets.
Experience leading customer segmentation and targeting across HCP, patient and/or payer audiences, integrated channel planning and insight-driven resource allocation.
Strong project management skills with the ability to manage multiple high-priority workstreams and meet tight deadlines.
Executive-level communication, analytical and influencing skills, with a demonstrated track record of shaping commercial strategy and building alignment at senior levels across functions.
Experience navigating MLR review processes and working closely with Legal, Regulatory, Compliance and Medical Affairs partners.
Ability to travel up to approximately 30%, including national medical congresses, customer engagements, agency meetings and internal team meetings.

Nice To Haves

Immunology, inflammation and/or rare disease experience.
Experience with rheumatology, gastroenterology, systemic autoimmune disease or B-cell mediated conditions.
Brand, HCP, patient and/or account marketing experience across multiple customer audiences, brands or indications.
Familiarity with modular content strategy, Veeva Vault PromoMats or equivalent platforms.
Field experience or close partnership with customer-facing teams.

Responsibilities

Own the brand strategy for obexelimab in IgG4-RD across all customer audiences, including product positioning, messaging, market differentiation and core strategic choices — serving as the ultimate decision-maker and brand steward.
Lead and represent Marketing on the Obexelimab US Brand Team, driving strategic alignment across brand, launch and all cross-functional workstreams and holding accountability for brand consistency and direction across audiences.
Drive launch-readiness planning end-to-end, including milestone ownership, resource prioritization, launch governance and senior-leadership alignment on brand strategy and commercial investment.
Translate market research, advisory board feedback, competitive intelligence and field insights into actionable brand strategies and tactical plans across customer segments.
Establish core brand messaging for the full customer base, including key specialists, KOLs, account-based stakeholders and patient/caregiver audiences, ensuring a consistent and compelling brand voice across all segments.
Lead development of disease education and promotional materials for all customer audiences from concept through review and approval, ensuring alignment with brand strategy and regulatory requirements.
Build the market development strategy, including congress, advisory board, speaker bureau and customer engagement priorities across HCP, patient and community audiences in partnership with Strategic Engagement and Medical Affairs.
Partner with Sales and Training to ensure field teams are equipped with clear messages, useful tools and practical customer engagement resources.
Lead customer segmentation and targeting efforts across HCP, patient and payer audiences to optimize outreach, precision and impact across channels.
Define the integrated channel strategy for all customer audiences in partnership with digital, analytics and agency partners, including modular content, channel planning and connected customer touchpoints.
Use data and analytics to guide investment choices, refine customer strategy and optimize budget allocation across tactics and segments.
Identify opportunities to strengthen HCP understanding of IgG4-RD and obexelimab's potential role through credible, compliant and customer-centered education.
Ensure strong collaboration across Marketing, Sales, Access & Trade, Strategic Engagement, Analytics, Medical Affairs, Compliance, Legal, Regulatory and Patient Support Services.
Lead agency partners to deliver high-quality work on time and within budget, with clear briefs, roles, timelines and expectations.
Prioritize investment opportunities and secure budget alignment from senior leadership for strategic brand and commercial marketing initiatives.
Champion cross-functional teamwork, urgency, continuous learning and high standards of execution consistent with Zenas' TRUE Innovation values.