Senior Associate Scientist

Pfizer • Bothell, WA

21h • Onsite

About The Position

At Pfizer, our purpose is to deliver breakthroughs that change patients’ lives. As a Senior Associate Scientist Biology, you will be at the forefront of our mission, contributing to the development of innovative therapies and vaccines that have the potential to transform patient care. Reporting to the Research & Development division, you will leverage advanced science and cutting-edge technologies to make a tangible impact on global health. Your work will be instrumental in ensuring drug safety and efficacy, supporting clinical trials, and accelerating the delivery of top-tier medicines to patients worldwide. In this role, you will be part of Pharmaceutical Research and Development, supporting Pfizer’s biotherapeutics portfolio, contributing to the development of parenteral formulations for antibody–drug conjugates (ADCs) and monoclonal antibodies (mAbs), with potential to work on proteins and other biologics. You will perform formulation development and analytical characterization of candidate molecules and formulations using a range of biophysical and biochemical techniques. You will also support drug product manufacturing process development and be responsible for data compilation, presentations, and technical report writing. A strong foundation in scientific principles and best practices will enable you to meet critical deadlines and deliver high‑quality work. As a technical contributor, you will assess assigned tasks and make informed decisions through the direct application of your expertise. Your dedication will help Pfizer reach new milestones and ultimately improve the lives of patients worldwide.

Requirements

• Bachelor’s degree (BA/BS) in Biochemistry, Chemical or Biochemical Engineering, Pharmacy, Chemistry, Biology, or a related discipline with at least 2 years of relevant experience, or a Master’s degree in a relevant discipline with 0+ years of experience.
• Hands‑on laboratory experience with a variety of analytical techniques, which may include UPLC (SEC, IEX), capillary gel electrophoresis (CGE), imaged capillary electrophoresis (iCE), and spectroscopic methods.
• Excellent problem‑solving and critical‑thinking skills used to solve scientific problems using experimental techniques, with contemporaneous recording of experimental details and data in an electronic laboratory notebook (ELN).
• Ability to effectively communicate (oral and written) and collaborate, with experience working within multidisciplinary project teams
• Strong attention to detail and a high level of accuracy in scientific work and documentation
• Strong organizational and time‑management skills.
• Proficiency with general computer software, including word processing, spreadsheets, and presentation tools.
• Permanent work authorization in the United States.

Nice To Haves

• Experience in formulation and process development for lyophilized ADC and/or mAb drug product
• Hands-on experience with analytical techniques such as SE‑UPLC, RP‑UPLC, Karl Fischer titration, differential scanning calorimetry (DSC), freeze-drying microscopy (FDM), dynamic light scattering (DLS), etc.
• Knowledge of current U.S. and global regulatory requirements, including FDA and ICH guidance.
• Experience using common AI‑enabled tools, including generative technologies such as ChatGPT or Microsoft Copilot, to support problem solving and enhance productivity.

Responsibilities

• Support development of parenteral formulations and manufacturing processes for ADCs and mAbs.
• Characterize candidate molecules and formulations to establish stability profiles using a broad range of biophysical and biochemical techniques (e.g., U/HPLC, imaged capillary electrophoresis (iCE), capillary gel electrophoresis (CGE), spectroscopy).
• Assist with scale-up of drug product processes (fluid handling, sterilizing filtration, lyophilization) from bench to pilot scale and support technology transfer to manufacturing facilities.
• Collaborate within team and cross‑functionally to advance formulation optimization and candidate progression.
• Summarize data, prepare presentations, and author technical reports to communicate results.

Benefits

• 401(k) plan with Pfizer Matching Contributions
• additional Pfizer Retirement Savings Contribution
• paid vacation
• holiday and personal days
• paid caregiver/parental and medical leave
• health benefits to include medical, prescription drug, dental and vision coverage.
• Relocation assistance may be available based on business needs and/or eligibility.

What This Job Offers

• Job Type: Full-time
• Career Level: Senior