Senior Associate Scientist

Pfizer • Bothell, WA

15h • Onsite

About The Position

Pfizer's purpose is to deliver breakthroughs that change patients’ lives. At the core of this mission is Research and Development, where we strive to transform advanced science and technologies into the most impactful therapies and vaccines. Whether you are involved in discovery sciences, ensuring drug safety and efficacy, or supporting clinical trials, you will leverage cutting-edge design and process development capabilities. This collaborative effort accelerates the delivery of best-in-class medicines to patients globally, fulfilling Pfizer’s commitment to making a significant difference in healthcare. In this role, you will be part of Pharmaceutical Research and Development, supporting Pfizer’s biotherapeutics portfolio, contributing to the development of parenteral formulations for antibody–drug conjugates (ADCs) and monoclonal antibodies (mAbs), with potential to work on proteins and other biologics. You will perform formulation development and analytical characterization of candidate molecules and formulations using a range of biophysical and biochemical techniques. You will also support drug product manufacturing process development and be responsible for data compilation, presentations, and technical report writing. A strong foundation in scientific principles and best practices will enable you to meet critical deadlines and deliver high‑quality work. As a technical contributor, you will assess assigned tasks and make informed decisions through the direct application of your expertise. Your dedication will help Pfizer reach new milestones and ultimately improve the lives of patients worldwide.

Requirements

• Bachelor’s degree (BA/BS) in Biochemistry, Chemical or Biochemical Engineering, Pharmacy, Chemistry, Biology, or a related discipline with at least 2 years of relevant experience, or a Master’s degree with 0+ years of relevant experience.
• Hands‑on laboratory experience with a variety of analytical techniques, which may include UPLC (SEC, IEX), capillary gel electrophoresis (CGE), imaged capillary electrophoresis (iCE), and spectroscopic methods.
• Excellent problem‑solving and critical‑thinking skills used to solve scientific problems using experimental techniques, with contemporaneous recording of experimental details and data in an electronic laboratory notebook (ELN).
• Ability to effectively communicate (oral and written) and collaborate, with experience working within multidisciplinary project teams
• Strong attention to detail and a high level of accuracy in scientific work and documentation
• Strong organizational and time‑management skills.
• Proficiency with general computer software, including word processing, spreadsheets, and presentation tools.
• Permanent work authorization in the United States.

Nice To Haves

• Experience in formulation and process development for lyophilized ADC and/or mAb drug product
• Hands-on experience with analytical techniques such as SE‑UPLC, RP‑UPLC, Karl Fischer titration, differential scanning calorimetry (DSC), freeze-drying microscopy (FDM), dynamic light scattering (DLS), etc.
• Knowledge of current U.S. and global regulatory requirements, including FDA and ICH guidance.
• Experience using common AI‑enabled tools, including generative technologies such as ChatGPT or Microsoft Copilot, to support problem solving and enhance productivity.

Responsibilities

• Support development of parenteral formulations and manufacturing processes for ADCs and mAbs.
• Characterize candidate molecules and formulations to establish stability profiles using a broad range of biophysical and biochemical techniques (e.g., U/HPLC, imaged capillary electrophoresis (iCE), capillary gel electrophoresis (CGE), spectroscopy).
• Assist with scale-up of drug product processes (fluid handling, sterilizing filtration, lyophilization) from bench to pilot scale and support technology transfer to manufacturing facilities.
• Collaborate within team and cross‑functionally to advance formulation optimization and candidate progression.
• Summarize data, prepare presentations, and author technical reports to communicate results.

Benefits

• 401(k) plan with Pfizer Matching Contributions
• additional Pfizer Retirement Savings Contribution
• paid vacation
• holiday and personal days
• paid caregiver/parental and medical leave
• health benefits to include medical, prescription drug, dental and vision coverage
• Relocation assistance may be available based on business needs and/or eligibility.

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level