Senior Associate Scientist, High-throughput Molecular Biologist
About The Position
The High-throughput Screening (HTS) team is looking for a highly motivated molecular biology expert to support development and evaluation of vaccine candidates. In this position, you will apply strong molecular biology expertise to perform cell-based expression assays and automated screening workflows in a BSL-2 laboratory environment. You will help expand high-throughput capabilities by collaborating with automation specialists, generating high-quality experimental data, and supporting the design, cloning, and validation of vaccine constructs. Through close collaboration with your teammates and cross-functional teams, your efforts will help ensure timely, data-driven advancement of vaccine programs in a dynamic and collaborative setting.
Requirements
- Bachelor’s degree (BA/BS) in a relevant scientific discipline (e.g., Biology, Cell Biology, Molecular Biology)
- 3 to 5 years of experience in an academic or biopharmaceutical research environment OR Masters degree with 0 to 3 years of experience.
- Demonstrated proficiency in molecular biology techniques, including in vitro transcription, RNA analysis, and cell‑based assays
- Hands‑on experience working with mammalian cell culture systems and applying aseptic techniques in a laboratory setting
- Ability to independently design, execute, and analyze experiments, with confidence presenting and explaining data outcomes
- Strong attention to detail and commitment to data quality and documentation standards
- Proven ability to work collaboratively in a fast‑paced, team‑oriented environment
- Highly organized, detail‑oriented, with strong written and verbal communication skills
- Proficiency in scientific computing and documentation tools, including Microsoft Excel, PowerPoint, SharePoint, and GraphPad Prism
Nice To Haves
- Experience operating and/or supporting Hamilton STAR automation platforms, including method execution or development
- Experience operating or troubleshooting automation instruments such as KingFisher Apex
- Hands‑on experience with molecular cloning and sequencing analysis
- Familiarity with LIMS, GeneData, or similar data management platforms
Responsibilities
- Perform RNA synthesis, characterization, and analytical assessments to support preclinical evaluation of vaccine candidates
- Design, execute, and troubleshoot cell‑based assays to evaluate in vitro expression of vaccine candidates
- Support the development of Hamilton STAR methods in collaboration with automation expert, translating manual molecular biology workflows into automation‑compatible, high‑throughput screening methods
- Operate Hamilton STAR liquid handling platforms to execute automated workflows that enable efficient screening of vaccine candidates
- Independently collect, analyze, interpret, and summarize experimental data, ensuring accuracy, reproducibility, and scientific rigor
- Communicate experimental results and progress updates to team members and senior leadership in a clear and timely manner
- Maintain accurate and well‑organized inventories of reagents and biological samples to support high‑throughput operations
- Ensure high‑quality documentation and reporting in accordance with SOPs and Pfizer Laboratory Notebook Policy requirements
Benefits
- 401(k) plan with Pfizer Matching Contributions
- Additional Pfizer Retirement Savings Contribution
- Paid vacation
- Paid holiday and personal days
- Paid caregiver/parental and medical leave
- Health benefits to include medical, prescription drug, dental and vision coverage
- Relocation support available
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What This Job Offers
Job Type
Full-time
Career Level
Senior
