Molecular Biologist / Research Scientist

Proto-TownLockhart, TX

About The Position

We are building an automated biology platform and are looking for a molecular biologist / research scientist to handle the core wet lab work, including selection design, library construction, and readouts. The role involves running end-to-end workflows from library preparation through selection to characterized hits. The successful candidate will design selection strategies, including stringency schedules, bottlenecks, and counter-selections, as well as design FACS sorting and screening strategies and interpret population trajectories across rounds.

Requirements

  • Cell culture: hands-on experience, ideally with yeast.
  • Molecular cloning: fundamentals (PCR amplification, Gibson assembly, Golden Gate assembly, transformations); experience with sequencing services.
  • Flow cytometry/FACS: gating strategies, staining, sample loading.

Nice To Haves

  • Yeast genetics and surface display
  • OrthoRep or other continuous hypermutation systems
  • phage display or PACE
  • SPR/BLI
  • NGS library prep and analysis
  • protein expression and purification
  • Opentrons, Hamilton, Tecan, or eVOLVER-class hardware.

Responsibilities

  • Run end to end workflows, library through selection to characterized hits
  • Design selection strategy: stringency schedules, bottlenecks, counter-selections
  • Design FACS sorting and screening strategies, and interpret population trajectories across rounds
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