Senior Accounting Manager

BillionToOne•Menlo Park, CA

6d•$174,068 - $206,706

About The Position

The Senior Accounting Manager will oversee the accounting operations of BillionToOne, a newly public company in its first full year of SOX 404(b) compliance. Reporting to the Director of Accounting, this role manages the month-end and quarter-end close, owns the integrity of the general ledger, and serves as a named control owner within the SOX framework. The role leads a team of GL and AP accountants, serves as a primary day-to-day contact for external auditors, and owns the monthly management reporting package, including flux analysis and cost-per-test economics. The company seeks a candidate with experience in a fast-paced, post-IPO environment who can drive operational and process improvements. BillionToOne is a molecular diagnostics company focused on making powerful, accurate diagnostic tests accessible. Its products serve prenatal and cancer diagnostics, using QCT molecular counting technology to enhance disease detection resolution. The company is headquartered in Menlo Park, with facilities in Union City, California, and a lab planned to open in Austin, Texas in 2027.

Requirements

8–10+ years of progressive accounting experience, including 3+ years managing the close and leading a team of direct reports.
CPA required, with deep US GAAP fluency.
Hands-on SOX 404(b) experience as a control owner, including familiarity with control narratives in functional areas outside accounting and reporting, IPE requirements, and deficiency remediation.
Strong NetSuite experience, including the ability to query the system directly using saved searches.
Advanced Excel and analytical abilities.
Excellent communication and interpersonal skills, with the ability to collaborate effectively across departments.
Bachelor’s degree in Accounting, Finance, or a related field.

Nice To Haves

Post-IPO experience is strongly preferred.
Experience in life sciences, diagnostics, or another high-growth regulated industry.
Big 4 or national audit firm experience.
FloQast, Expensify, and Workiva experience.
SuiteQL experience.

Responsibilities

Manage the month-end and quarter-end close on a dependency-gated FloQast calendar, including the journal entry control log, reconciliation sign-offs, and close checklist completion; compress the close timeline while improving quality and audit readiness.
Own general ledger accuracy and integrity in NetSuite, including review of recurring and non-standard journal entries, balance sheet reconciliations across the account population, and resolution of posting and configuration issues.
Serve as a named owner and reviewer for financial reporting, general ledger, and close-cycle SOX controls; maintain control narratives and supporting documentation, ensure IPE meets completeness and accuracy standards, remediate deficiencies, and coordinate deliverables with business partners.
Serve as a day-to-day contact for the Big 4 external auditor and consulting advisors; manage PBC requests, walkthrough support, sample pulls, and interim and year-end fieldwork.
Own the monthly management reporting package, including month-over-month flux analysis by functional area, cost-per-test analytics for prenatal and oncology products, and a management summary for the CFO and leadership team.
Lead, mentor, and develop GL and AP accountants across general ledger, fixed assets, accounts payable, and payroll; set expectations, establish review discipline, and develop the team’s technical depth.
Operationalize technical accounting conclusions, including ASC 842 lease accounting and embedded lease assessment, ASC 730 R&D cost treatment, and self-funded health plan IBNR reserves.
Improve close and accounting processes to increase speed and efficiency while demonstrating operational compliance.
Provide senior oversight of the vendor master and disbursement control environment, partnering with Supply Chain to support and govern procurement across the AP and payment cycle.

Benefits

Multiple medical benefit options; employee premiums are paid 100% for select plans, and dependents are covered up to 80%.
Family Bonding Leave for eligible employees: 16 weeks, paid at 100%.
Supplemental fertility benefits coverage.
Retirement savings program with a 4% company match.
Paid time off increases with tenure.
Latest hardware, including laptops, lab equipment, and facilities.
Free daily on-site lunches.
On-campus state-of-the-art gym and restaurant.
Free on-site EV charging.
Annual bonus eligibility.
New-hire equity grant of up to $110,000 at grant value, vesting over four years, plus annual equity refresh grants equal in value to the new-hire grant.
Medical and dental coverage.