Scientist – Metabolite ID and Profiling

Labcorp•Madison, WI

9d•Onsite

About The Position

Labcorp is seeking a Scientist I – Metabolite ID and Profiling to join its team in Madison, Wisconsin. The role performs day-to-day technical management of intermediate-complexity studies, developing and applying qualitative LC-HRMS methods to identify metabolites across species and biological matrices. It involves interpreting MS/MS fragmentation pathways for metabolite structure elucidation and applying radiolabeled isotope techniques for metabolite profiling and quantitation. The scientist profiles and elucidates drug-candidate metabolites using LC/MS, radiodetection, and other appropriate techniques. The role designs, conducts, and reports studies that meet scientific, regulatory, and client requirements; reviews project and result validity, sometimes with assistance from more experienced scientists; evaluates data for reports and experimental modifications; and writes comprehensive reports. Project management includes client interaction, and the scientist may co-author scientific papers and posters. Occasional mentorship and guidance are provided to develop general expertise in the field.

Requirements

Bachelor of Science degree and at least 7 years of laboratory experience, or Master of Science degree and at least 3 years of laboratory experience.
At least 3 years of experience with Liquid Chromatography–Mass Spectrometry (LC-MS).
Knowledge of GLP and regulatory guidelines.
Ability to organize and manage projects effectively and in a timely manner.
Ability to conduct literature reviews.
Ability to perform data interpretation and report writing for studies effectively.

Nice To Haves

Ph.D.

Responsibilities

Perform day-to-day technical management of studies.
Develop and apply qualitative LC-HRMS methods to identify metabolites in multiple species and biological matrices.
Interpret MS/MS fragmentation pathways for metabolite structure elucidation.
Apply radiolabeled isotope techniques for metabolite profiling and quantitation.
Profile and elucidate drug-candidate metabolites using LC/MS, radiodetection, and other appropriate techniques.
Design, conduct, and report intermediate-complexity studies that meet scientific, regulatory, and client requirements.
Review the technical validity of projects and results, occasionally with help from more experienced scientists.
Evaluate data for report preparation and experimental modification, as applicable.
Write comprehensive study reports.
Manage projects, including client interaction.
Co-author scientific papers and posters.
Provide occasional mentorship and guidance to develop general expertise in the field.