Scientist – Metabolite ID and Profiling

Labcorp•Madison, WI

11d

About The Position

Labcorp is seeking a Scientist I – Metabolite ID and Profiling to join its team in Madison, Wisconsin. The role performs day-to-day technical management of intermediate-complexity studies and supports metabolite identification and profiling for drug candidates. Work includes qualitative LC-HRMS development and application to identify metabolites across multiple species and biological matrices, interpretation of MS/MS fragmentation for structural elucidation, and use of radiolabeled isotope techniques for profiling and metabolite quantitation. The scientist designs, conducts, and reports studies in accordance with scientific, regulatory, and client requirements. Responsibilities include evaluating data, preparing reports, modifying experiments as appropriate, reviewing project and result validity, and managing client interactions. The role may provide occasional mentorship and guidance, and includes opportunities to co-author scientific papers and posters. Labcorp provides ADME services supporting drug discovery and development programs.

Requirements

Bachelor of Science degree and 7 or more years of laboratory experience, or Master of Science degree and 3 or more years of laboratory experience.
3 or more years of experience with Liquid Chromatography–Mass Spectrometry (LC-MS).
Knowledge of GLP and regulatory guidelines.
Ability to organize and manage projects effectively and in a timely manner.
Ability to conduct literature reviews.
Ability to perform data interpretation and report writing for studies effectively.

Nice To Haves

Ph.D.

Responsibilities

Perform day-to-day technical management of studies.
Develop and apply qualitative LC-HRMS methods to identify metabolites in multiple species and biological matrices.
Interpret MS/MS fragmentation pathways for metabolite structure elucidation.
Apply radiolabeled isotope techniques for profiling and metabolite quantitation.
Profile and elucidate the structures of drug candidate metabolites using LC/MS, radiodetection, and other appropriate techniques.
Design, conduct, and report studies to meet scientific, regulatory, and client requirements.
Review the technical validity of projects and results, with occasional assistance from more experienced scientists.
Evaluate data for report preparation and experiment modification, as applicable, and write comprehensive reports.
Manage projects, including client interaction.
Co-author scientific papers and posters.
Provide occasional mentorship and guidance to develop general expertise in the field.