Scientist

Guidehouse•Bethesda, MD

6h•$98,000 - $163,000•Onsite

About The Position

We are currently searching for a Scientist to provide support services to satisfy the overall operational objectives of the National Heart, Lung, and Blood Institute (NHLBI) . This is a full-time, on-site opportunity in Bethesda, MD. Develop and oversee research projects aiming at identifying novel cyclic peptides that target biological targets of interest. Prepare mRNA peptide display libraries for screening. Synthesize putative hits and optimize confirmed leads. Coordinate efforts with biological collaborators. Maintain equipment related to library generation and screening. Support the development and implementation of comprehensive documentation of modeling approaches and processes. Support the establishment, maintenance, and oversight of data governance standards for applicable systems. Resolve operational challenges and problems without assistance from senior staff. Provide scientific and technical expertise to all visiting fellows, post-docs, and technicians. Provide advice and guidance in their day-to-day activities. Collaborate with the lab staff in planning, coordinating and reviewing the laboratory’s programs, resources and activities. Participate in the laboratory’s review of future proposals for resource allocations. Design and conduct experiments and studies that require the application of a broad professional knowledge of scientific theories and principles. Evaluate and interpret research results from studies. Manage scientific equipment and resources (e.g. chemicals and disposables) including acquisition, documentation and storage. Assist the lab staff in the creation and preparation of a variety of documents required by the lab’s scientific activities (e.g., CRADAs, Material Transfer Agreements, Patent Applications, Quadrennial review). Review, edit, and as needed, write first drafts of papers, posters and manuscripts produced within the laboratory for consistency of the research agenda, adherence to any applicable scientific policies, and clarity of presentation of data and other scientific information. Follow existing safety procedures including the use of personal protective equipment.

Requirements

Ph.D. in Medicinal Chemistry or related field
Minimum SIX (6) years of experience in Chemistry.
Expertise in synthesizing novel compounds and analytically characterizing them.
Ability to manage and coordinate high-priority short- and long-term projects and studies in a fast-paced environment
Must be able to obtain and maintain a Federal or DoD Public Trust.
Candidates must receive approved adjudication of their Public Trust prior to onboarding with Guidehouse.
Candidates with an active Public Trust or existing suitability are preferred.

Nice To Haves

Prefer ten+ (10) years of experience
Excellent analytical, organizational and time management skills
Strong communication skills, both oral and written

Responsibilities

Develop and oversee research projects aiming at identifying novel cyclic peptides that target biological targets of interest.
Prepare mRNA peptide display libraries for screening.
Synthesize putative hits and optimize confirmed leads.
Coordinate efforts with biological collaborators.
Maintain equipment related to library generation and screening.
Support the development and implementation of comprehensive documentation of modeling approaches and processes.
Support the establishment, maintenance, and oversight of data governance standards for applicable systems.
Resolve operational challenges and problems without assistance from senior staff.
Provide scientific and technical expertise to all visiting fellows, post-docs, and technicians.
Provide advice and guidance in their day-to-day activities.
Collaborate with the lab staff in planning, coordinating and reviewing the laboratory’s programs, resources and activities.
Participate in the laboratory’s review of future proposals for resource allocations.
Design and conduct experiments and studies that require the application of a broad professional knowledge of scientific theories and principles.
Evaluate and interpret research results from studies.
Manage scientific equipment and resources (e.g. chemicals and disposables) including acquisition, documentation and storage.
Assist the lab staff in the creation and preparation of a variety of documents required by the lab’s scientific activities (e.g., CRADAs, Material Transfer Agreements, Patent Applications, Quadrennial review).
Review, edit, and as needed, write first drafts of papers, posters and manuscripts produced within the laboratory for consistency of the research agenda, adherence to any applicable scientific policies, and clarity of presentation of data and other scientific information.
Follow existing safety procedures including the use of personal protective equipment.

Benefits

Medical, Rx, Dental & Vision Insurance
Personal and Family Sick Time & Company Paid Holidays
Parental Leave
401(k) Retirement Plan
Group Term Life and Travel Assistance
Voluntary Life and AD&D Insurance
Health Savings Account, Health Care & Dependent Care Flexible Spending Accounts
Transit and Parking Commuter Benefits
Short-Term & Long-Term Disability
Tuition Reimbursement, Personal Development, Certifications & Learning Opportunities
Employee Referral Program
Corporate Sponsored Events & Community Outreach
Care.com annual membership
Employee Assistance Program
Supplemental Benefits via Corestream (Critical Care, Hospital Indemnity, Accident Insurance, Legal Assistance and ID theft protection, etc.)