Scientist
About The Position
Join Amgen’s Mission of Serving Patients At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do. Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity-related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career. Scientist What you will do Let’s do this. Let’s change the world. Amgen is seeking a Scientist to join the Pathology Laboratory within the Translational Safety & Risk Sciences (TSRS) Department in South San Francisco, California. The Scientist will develop and apply tissue-based assays, including multiplex assays and digital image analysis, to support target expression studies, preclinical model development, pharmacodynamics, efficacy, and biomarker discovery.
Requirements
- Doctorate degree
- Master’s degree and 2+ years of relevant research and industry experience
- Bachelor’s degree and 4 years of relevant research and industry experience
- Experience analyzing pathology imaging data, including H&E, IHC, multiplex immunofluorescence, and/or spatial transcriptomics.
- Strong communication, organizational, and collaboration skills in multidisciplinary scientific environments.
Nice To Haves
- PhD or master’s degree in cell biology, molecular biology, or related discipline.
- Two or more years of molecular pathology experience, preferably in an industry setting.
- Demonstrated expertise in pathology-based methods, including IHC, multiplex IHC, ISH and immunofluorescence imaging.
- Experience with digital pathology and image analysis, preferably using HALO and/or Visiopharm.
- Experience with automated staining platforms, such as Ventana, Leica Bond, or IntelliPATH, is preferred.
- Ability to manage multiple projects and priorities simultaneously.
- Excellent written and verbal communication skills.
- Familiarity with whole-slide imaging and digital pathology platforms, such as HALO or Visiopharm, is preferred.
- Understanding of machine-learning methods for image segmentation, classification, detection, and representation learning.
Responsibilities
- Develop, optimize, validate, and standardize histopathology assays using FFPE samples, including single-plex and multiplex immunohistochemistry (IHC) and in situ hybridization (ISH) in colorimetric and immunofluorescent formats.
- Use imaging modalities and digital pathology tools to generate, analyze, and interpret tissue-based data for target qualification, pharmacodynamic and efficacy assessments, and biomarker development.
- Collaborate with pathologists, research investigators, and translational teams to deliver high-quality data supporting mechanism-of-action studies, in vivo model development, and toxicity assessments across therapeutic areas.
- Maintain clear, complete documentation and communicate results through laboratory information systems, databases, and team presentations.
Benefits
- A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
- A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
- Stock-based long-term incentives
- Award-winning time-off plans
- Flexible work models where possible.
Stand Out From the Crowd
Upload your resume and get instant feedback on how well it matches this job.
What This Job Offers
Job Type
Full-time
Career Level
Senior
Education Level
Ph.D. or professional degree
