Scientist – Inflammation Research

Amgen • Thousand Oaks, CA

2d

About The Position

The Scientist – Inflammation Research performs in vitro and in vivo experiments to study drug targets, including work with organoid and air-liquid-interface primary cell cultures and mouse models of inflammatory disease. The role also analyzes lung epithelium function, repair, and regeneration and collaborates with a research team across multiple Amgen functional areas.

The Scientist generates experimental data for target identification, validation, and progression of inflammation research programs; proposes respiratory disease drug targets using human genetics, experimental findings, and published literature; and uses AI-driven approaches to develop mechanistic insights, refine therapeutic hypotheses, and inform experimental design. The role requires scientific rigor, urgency, and adaptability, and includes publishing and presenting research.

Requirements

• Doctorate degree; or a Master’s degree and 2 years of Biological Sciences or Biomedical Sciences experience; or a Bachelor’s degree and 4 years of Biological Sciences or Biomedical Sciences experience.

Nice To Haves

• PhD with a strong background and research experience in epithelial biology and inflammation.
• Experience performing both in vitro and in vivo experiments.
• Expertise in 2D and 3D primary cell cultures, co-cultures, human tissue cultures, and mouse disease models.
• Technical expertise in mouse respiratory disease models and measurement of pulmonary mechanics.
• Strong publication record or significant contributions to therapeutic development programs.

Responsibilities

• Perform in vitro and in vivo experiments.
• Generate high-quality experimental data to support target identification, validation, and progression of inflammation research programs.
• Propose drug targets for respiratory diseases by integrating human genetics, in vitro and in vivo studies, and published literature.
• Use AI-driven approaches to generate mechanistic insights, refine therapeutic hypotheses, and guide experimental design.
• Analyze lung epithelium function, repair, and regeneration.
• Publish research and present at conferences.
• Collaborate with a research team from multiple Amgen functional areas.

Benefits

• Retirement and Savings Plan with generous company contributions
• Group medical coverage
• Dental coverage
• Vision coverage
• Life insurance
• Disability insurance
• Flexible spending accounts
• Discretionary annual bonus program, or a sales-based incentive plan for field sales representatives
• Stock-based long-term incentives
• Award-winning time-off plans
• Flexible work models where possible
• Career development opportunities

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level