Scientist – Inflammation Research

Amgen • Thousand Oaks, CA

3d • $115,393 - $156,121

About The Position

The Scientist will conduct in vitro and in vivo research to evaluate drug targets, using organoid and air-liquid-interface primary cell cultures and mouse models of inflammatory disease. The role includes analyzing lung epithelium function, repair, and regeneration, and collaborating with researchers across multiple Amgen functional areas.

The Scientist will generate experimental evidence to support target identification, validation, and progression of inflammation research programs; propose respiratory disease targets by integrating human genetics, experimental findings, and published literature; and use AI-driven approaches to develop mechanistic insights, refine therapeutic hypotheses, and guide experimental design. The role also includes publishing and presenting research and working with scientific rigor, urgency, and adaptability in a dynamic environment.

Requirements

• Doctorate degree; or a master's degree and 2 years of Biological Sciences or Biomedical Sciences experience; or a bachelor's degree and 4 years of Biological Sciences or Biomedical Sciences experience.

Nice To Haves

• PhD with a strong background and research experience in epithelial biology and inflammation.
• Experience performing both in vitro and in vivo experiments.
• Expertise in 2D and 3D primary cell cultures, co-cultures, human tissue cultures, and mouse disease models.
• Technical expertise in mouse respiratory disease models and measurement of pulmonary mechanics.
• Strong publication record or significant contributions to therapeutic development programs.

Responsibilities

• Perform in vitro and in vivo experiments.
• Generate high-quality experimental data to support target identification, validation, and progression of inflammation research programs.
• Propose drug targets for respiratory diseases by integrating human genetics, in vitro and in vivo studies, and published literature.
• Use AI-driven approaches to generate mechanistic insights, refine therapeutic hypotheses, and guide experimental design.
• Analyze lung epithelium function, repair, and regeneration.
• Publish and present at conferences.
• Collaborate with a research team across multiple Amgen functional areas.
• Balance scientific rigor with urgency and adaptability in a dynamic research environment.

Benefits

• Comprehensive employee benefits package, including a Retirement and Savings Plan with company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.
• Discretionary annual bonus program.
• Stock-based long-term incentives.
• Award-winning time-off plans.
• Flexible work models where possible.
• Career development opportunities.

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level
• Education Level: Ph.D. or professional degree