Scientist, Sequencing and Plate-Based Assays
About The Position
Bristol Myers Squibb is seeking a motivated and detail-oriented (Senior) Scientist to join its Analytical Development team. The role develops new analytical methods to characterize RNA therapeutics and supports routine and non-routine analytical testing for the company's in vivo non-viral drug discovery and development pipeline. The ideal candidate has hands-on laboratory experience, a strong scientific foundation, and a commitment to data quality and compliance. The scientist develops NGS and Sanger sequencing, qPCR, and plate-based assays such as ELISA and MSD, while exploring new techniques and technologies for RNA characterization. The role also includes analyzing and reporting experimental data, contributing to regulatory documents and method protocols, training junior team members, and carrying out compliant laboratory work. The scientist maintains laboratory equipment, follows safety and environmental health requirements, and collaborates with research, process development, and formulations teams.
Requirements
- PhD in Biochemistry, Chemistry, Biology, Pharmaceutical Sciences, or a related scientific discipline.
- 3–8 years of hands-on laboratory experience, preferably with RNA and/or LNPs, including academic research, internships, or industry roles.
- Proficiency with NGS and Sanger sequencing, including sample preparation, instrumentation, and data analysis.
- Proficiency with plate-based assays, including qPCR, digital PCR, ELISA, and others.
- Ability to work independently and manage multiple priorities in a fast-paced environment while maintaining accuracy and attention to detail.
- Ability to analyze data and present results to the team and the larger research community.
Nice To Haves
- Experience in a pharmaceutical or biopharmaceutical industry setting.
- Familiarity with QbD principles, ICH guidelines, analytical method lifecycle, GxP principles, and regulatory submission requirements.
- Experience with LIMS (Laboratory Information Management Systems).
- Experience with (bio)analytical method validation, such as per FDA or EMA guidelines.
- Working knowledge of statistical analysis tools such as GraphPad Prism, JMP, or Excel-based analysis.
- Experience with RNA characterization techniques such as RT-PCR, RNAseq, SEC, or CE.
Responsibilities
- Develop NGS and Sanger sequencing and qPCR methods for RNA therapeutics.
- Develop plate-based assays, such as ELISA and MSD.
- Explore new techniques and technologies to characterize RNA.
- Analyze, interpret, and summarize experimental data accurately, and prepare clear lab reports and technical summaries.
- Contribute to regulatory documents, method protocols, and reports.
- Train and mentor junior team members.
- Execute and document laboratory experiments according to established SOPs, protocols, and Good Laboratory Practice (GLP) standards.
- Maintain laboratory equipment, including calibration, troubleshooting, and coordination with vendors for preventive maintenance.
- Ensure compliance with safety regulations, environmental health and safety (EHS) guidelines, and BMS corporate policies.
- Contribute to cross-functional teams and collaborate with colleagues in research, process development, and formulations.
Benefits
- Comprehensive benefit plans, including wellbeing support, retirement and financial protection benefits, and medical, dental, vision, life, and disability insurance offerings.
- Flexible Time Off (FTO) without a set accrual limit for eligible U.S.-based exempt employees, subject to manager approval.
- 11 paid company holidays each year.
- For eligible non-exempt employees, RayzeBio employees, and employees located in Puerto Rico: 160 hours of paid vacation annually for new hires, subject to manager approval, 11 paid company holidays, and 3 optional holidays.
- Depending on eligibility, paid sick leave, up to two paid volunteer days per year, summer hours flexibility, and leaves of absence for medical, personal, parental, caregiver, bereavement, or military needs.
- Eligible employees receive an annual Global Shutdown between Christmas Day and New Year's Day.
- Potential eligibility for discretionary incentive cash and stock opportunities.
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What This Job Offers
Job Type
Full-time
Career Level
Mid Level
Education Level
Ph.D. or professional degree
