Scientist, Reproductive & Molecular Biology

Flagship Pioneering•Cambridge, MA

1d•Onsite

About The Position

We are seeking a Scientist with experience at the intersection of reproductive biology and molecular biology to help build the experimental foundation of the company’s scientific platform. As an early scientific team member, you will contribute to the development of core laboratory workflows spanning human gamete handling and molecular characterization, support the establishment of technical standards, and help execute the experimental strategy in close collaboration with senior scientists and leadership. We are looking for someone who is highly hands-on, adaptable, and excited to operate across disciplines. The ideal candidate brings a strong foundation from IVF or embryology laboratory environments, combined with experience in molecular biology techniques and a willingness to learn and implement new methods. This role requires attention to detail, comfort working with sensitive human samples, and a collaborative mindset suited for a fast-paced startup environment.

Requirements

Prior hands-on experience in IVF or embryology laboratory settings, including handling human gametes and performing procedures such as ICSI or related workflows
Ph.D. in biology, molecular biology, genetics, reproductive biology, or a related discipline strongly preferred; exceptional candidates with a Master’s degree / relevant hands-on experience will also be considered
Strong foundation in molecular biology techniques, with demonstrated ability to learn and adapt to new experimental methods
Demonstrated ability to execute and troubleshoot experiments independently, particularly in low-input or sensitive sample contexts
High attention to detail and commitment to quality, especially when working with human-derived samples
Comfort working in a fast-moving, early-stage startup environment with a collaborative and proactive mindset

Nice To Haves

Experience with RNA sequencing workflows; exposure to single-cell RNA sequencing is a plus

Responsibilities

Perform and support IVF laboratory procedures, including preparation and handling of human gametes in a BSL2 environment with strict adherence to quality and reproducibility standards
Execute workflows related to ART techniques such as intra-cytoplasmic sperm injection (ICSI) and related embryology methods, contributing to protocol optimization and standardization
Conduct molecular biology experiments, including nucleic acid extraction, amplification, and QC from low-input or sensitive samples
Contribute to the development and optimization of workflows for integrating embryology procedures with downstream molecular analyses
Support implementation of instrumentation, reagents, and workflows to enable robust and scalable experimental operations
Assist in transcriptomic workflows (e.g., RNA-seq), including sample preparation, library preparation, and coordination with sequencing efforts
Analyze and communicate experimental results clearly, troubleshoot challenges, and iterate on protocols
Collaborate across internal teams and incorporate feedback from external advisors into experimental plans